22 days in South America Itinerary

22 days in South America Itinerary

Created using Inspirock South America trip itinerary builder

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Route & dates

1
Bogota, Colombia
— 2 nights
2
Quito, Ecuador
— 1 night
3
Machu Picchu, Peru
— 1 night
4
Cusco, Peru
— 2 nights
5
Uyuni, Bolivia
— 1 night
6
San Pedro de Atacama, Chile
— 1 night
7
Santiago, Chile
— 1 night
8
Buenos Aires, Argentina
— 2 nights
9
Salta, Argentina
— 1 night
10
Iguazu National Park, Argentina
— 1 night
11
Foz do Iguacu, Brazil
— 1 night
12
Rio de Janeiro, Brazil
— 3 nights
13
Fernando de Noronha, Brazil
— 4 nights

2
nights
Bogota, Colombia

Colombia's heart and soul, Bogota has earned the nickname "Athens of South America" thanks to its abundance of universities, libraries, and lower-level schools.
Start off your visit on the 3rd (Mon): indulge in some culinary diversions at a local gastronomic tour and then admire the masterpieces at Museo Botero del Banco de la Republica. On the 4th (Tue), you'll have a packed day of sightseeing: take your sightseeing to a higher altitude at Monserrate, thenexamine the collection at Gold Museum (Museo del Oro), and then browse for treasures at El Cuchitril Second Hand Shop.

For traveler tips, maps, more things to do, and more tourist information, read our Bogota trip planner.

Dublin, Ireland to Bogota is an approximately 17.5-hour flight. The time zone changes from Greenwich Mean Time to Colombia Standard Time, which is usually a -5 hour difference. In May, Bogota is somewhat warmer than Dublin - with highs of °C and lows of °C. Finish up your sightseeing early on the 4th (Tue) so you can travel to Quito.

Things to do in Bogota

Museums Tours Nature
Find places to stay May 2 — 4:
Highlights from your plan
Food Tours
Gold Museum (Museo del Oro) ©
Gold Museum (Museo del Oro)
Monserrate ©
Monserrate

1
night
Quito, Ecuador

Quito ©
High in the Andean foothills, Quito remains one of the world's most photogenic capital cities, featuring two dramatic mountain ranges as its backdrop.
Kick off your visit on the 5th (Wed): see the interesting displays at Museo Camilo Egas, admire the landmark architecture of Fundacion Iglesia de la Compania, and then admire the landmark architecture of Iglesia y Convento de San Francisco.

For maps, where to stay, more things to do, and other tourist information, you can read our Quito trip itinerary planner.

Fly from Bogota to Quito in 6 hours. Alternatively, you can drive; or take a bus. Traveling from Bogota in May, expect somewhat warmer with lows of °C in Quito. Wrap up your sightseeing by early afternoon on the 5th (Wed) to allow time for travel to Machu Picchu.

Things to do in Quito

Historic Sites Museums
Find places to stay May 4 — 5:
Highlights from your plan
Fundacion Iglesia de la Compania ©
Fundacion Iglesia de la Compania
Iglesia y Convento de San Francisco ©
Iglesia y Convento de San Francisco
Museo Camilo Egas ©
Museo Camilo Egas

1
night
Machu Picchu, Peru

Machu Picchu ©
A symbol of the Incan civilization, the abandoned city of Machu Picchu represents a must-see on a Peru vacation.
Start off your visit on the 6th (Thu): steep yourself in history at Santuario Historico de Machu Picchu.

For where to stay, reviews, traveler tips, and tourist information, read our Machu Picchu online vacation planner.

Fly from Quito to Machu Picchu in 12 hours. Alternatively, you can drive; or do a combination of bus and car. Finish up your sightseeing early on the 6th (Thu) so you can travel to Cusco.

Things to do in Machu Picchu

Historic Sites
Find places to stay May 5 — 6:
Highlights from your plan
Santuario Historico de Machu Picchu ©
Santuario Historico de Machu Picchu

2
nights
Cusco, Peru

Cusco ©
Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.
Kick off your visit on the 7th (Fri): take in the architecture and atmosphere at Iglesia de la Compania de Jesus, thenadmire the masterpieces at Museo de Arte Precolombino, thensteep yourself in history at Sacsayhuaman, and finally take an in-depth tour of Museo Inka. Get ready for a full day of sightseeing on the 8th (Sat): delve into the distant past at Qorikancha, steep yourself in history at Plaza de Armas, and then steep yourself in history at Tipon.

For ratings, maps, more things to do, and other tourist information, refer to the Cusco day trip website.

You can do a combination of train and bus from Machu Picchu to Cusco in 4 hours. Other options are to take a train; or drive. In May, plan for daily highs up to °C, and evening lows to °C. Wrap up your sightseeing on the 8th (Sat) to allow time to travel to Uyuni.

Things to do in Cusco

Historic Sites Museums
Find places to stay May 6 — 8:
Highlights from your plan
Sacsayhuaman ©
Sacsayhuaman
Plaza de Armas ©
Plaza de Armas
Qorikancha ©
Qorikancha

1
night
Uyuni, Bolivia

Uyuni
Emptiness surrounds the desert outpost of Uyuni, the gateway to the world's largest salt flats.
To find other places to visit, reviews, where to stay, and other tourist information, read our Uyuni travel route planner.

You can fly from Cusco to Uyuni in 7 hours. Alternatively, you can drive; or do a combination of bus and taxi. Traveling from Cusco to Uyuni, you'll lose 1 hour due to the time zone difference. When traveling from Cusco in May, plan for much colder days in Uyuni, with highs around °C, while nights are about the same with lows around °C. You will leave for San Pedro de Atacama on the 9th (Sun).

Things to do in Uyuni

Tours Outdoors Wildlife
Find places to stay May 8 — 9:

1
night
San Pedro de Atacama, Chile

San Pedro de Atacama ©
Major archeological sites and a renowned museum remain the big draws in San Pedro de Atacama tourism, appealing to visitors interested in learning more about South America's pre-Columbian cultures.
Start off your visit on the 10th (Mon): take in the awesome beauty at Cordillera de la Sal, explore the striking landscape at Valle De La Luna, thenexplore the ancient world of Pukara de Quitor, and finally witness a stunning natural landmark at Geyser del Tatio.

For where to stay, maps, more things to do, and other tourist information, go to the San Pedro de Atacama holiday planning tool.

Traveling by combination of taxi and bus from Uyuni to San Pedro de Atacama takes 11.5 hours. Alternatively, you can drive. Expect warmer weather when traveling from Uyuni in May: highs in San Pedro de Atacama hover around °C, while lows dip to °C. Finish your sightseeing early on the 10th (Mon) to allow enough time to travel to Santiago.

Things to do in San Pedro de Atacama

Nature Parks Historic Sites
Find places to stay May 9 — 10:
Highlights from your plan
Geyser del Tatio ©
Geyser del Tatio
Valle De La Luna ©
Valle De La Luna
Pukara de Quitor ©
Pukara de Quitor

1
night
Santiago, Chile

Santiago ©
Santiago tourism thrives largely thanks to the city's big selection of cultural and entertainment options, including museums, theaters, restaurants, bars, and giant malls.
Kick off your visit on the 11th (Tue): take in the pleasant sights at Plaza de Armas, admire the striking features of Metropolitan Cathedral (Catedral Metropolitana), and then admire all the interesting features of Cerro Santa Lucia.

Plan a trip to Santiago easily and quickly by telling Inspirock to suggest an itinerary.

Fly from San Pedro de Atacama to Santiago in 5.5 hours. Alternatively, you can drive; or take a bus. Wrap up your sightseeing on the 11th (Tue) early enough to travel to Buenos Aires.

Things to do in Santiago

Parks
Find places to stay May 10 — 11:
Highlights from your plan
Cerro Santa Lucia ©
Cerro Santa Lucia
Plaza de Armas ©
Plaza de Armas

2
nights
Buenos Aires, Argentina

Buenos Aires ©
Cultural capital of South America, Buenos Aires remains one of the largest cities on the continent, serving as a point of departure for exploring the rest of the country.
On the 12th (Wed), take in nature's colorful creations at Jardin Japones, admire the natural beauty at Parque 3 de Febrero, thenexplore the world behind art at Museo Nacional de Bellas Artes, thenstroll the grounds of Cemiterio de Recoleta, and finally shop like a local with El Ateneo Grand Splendid. On the 13th (Thu), you'll have a packed day of sightseeing: admire the masterpieces at Museo de Arte Latinoamericano de Buenos Aires, take an in-depth tour of El Zanjon de Granados, thentake a stroll through Puerto Madero, and finally get a sense of history and politics at Casa Rosada.

For ratings, photos, traveler tips, and tourist information, refer to the Buenos Aires online attractions planner.

You can fly from Santiago to Buenos Aires in 6 hours. Other options are to drive; or take a bus. You'll lose 1 hour traveling from Santiago to Buenos Aires due to the time zone difference. In May, daytime highs in Buenos Aires are °C, while nighttime lows are °C. Finish up your sightseeing early on the 13th (Thu) so you can travel to Salta.

Things to do in Buenos Aires

Museums Parks Historic Sites
Find places to stay May 11 — 13:
Highlights from your plan
Puerto Madero ©
Puerto Madero
Cemiterio de Recoleta ©
Cemiterio de Recoleta
Parque 3 de Febrero ©
Parque 3 de Febrero

1
night
Salta, Argentina

Salta ©
Salta boasts a vibrant social life and array of informative museums appealing to visitors looking for a memorable cultural experience.
On the 14th (Fri), stop by El Gauchito Salteno, take an in-depth tour of MAAM - Museo de Arqueologia de Alta Montana de Salta, take in the spiritual surroundings of Basilica Menor San Francisco, explore the fascinating landscape at Salar del Diablo, thentake in the spiritual surroundings of Cathedral of Salta, and finally see the interesting displays at Salta Cabildo.

To see reviews, ratings, more things to do, and tourist information, read our Salta trip itinerary tool.

Fly from Buenos Aires to Salta in 4 hours. Alternatively, you can drive; or take a bus. Traveling from Buenos Aires in May, plan for a bit cooler nights in Salta, with lows around °C. Cap off your sightseeing on the 14th (Fri) early enough to travel to Iguazu National Park.

Things to do in Salta

Museums Nature Parks
Find places to stay May 13 — 14:
Highlights from your plan
Salta Cabildo ©
Salta Cabildo
Basilica Menor San Francisco ©
Basilica Menor San Francisco
Cathedral of Salta ©
Cathedral of Salta

1
night
Iguazu National Park, Argentina

Iguazu National Park ©
Iguazu National Park contains 672 sq km (259 sq mi) of fertile subtropical forests, but its main attraction is the majestic Iguazu Falls.
On the 15th (Sat), admire the sheer force of Salto Bernabe Mendez and then take in the dramatic scenery at Iguazu Falls.

To find traveler tips, more things to do, reviews, and tourist information, read our Iguazu National Park trip planner.

Traveling by flight from Salta to Iguazu National Park takes 4 hours. Alternatively, you can drive; or take a bus. Traveling from Salta in May, expect Iguazu National Park to be a bit warmer, temps between °C and °C. Finish your sightseeing early on the 15th (Sat) so you can drive to Foz do Iguacu.

Things to do in Iguazu National Park

Nature Parks Wildlife
Find places to stay May 14 — 15:
Highlights from your plan
Iguazu Falls ©
Iguazu Falls
Salto Bernabe Mendez ©
Salto Bernabe Mendez

1
night
Foz do Iguacu, Brazil

Foz do Iguacu ©
A gateway to the world-renowned Iguacu Falls, which spectacularly divide Brazil and Argentina, the modern, high-rise city of Foz do Iguacu can't help but play second fiddle to the natural wonder in its vicinity.
Kick off your visit on the 16th (Sun): see the interesting displays at Museu de Cera Dreamland, take in the dramatic scenery at Iguazu Falls, and then look for gifts at Artesanato Chocolate Caseiro Tres Fronteiras.

For ratings, more things to do, where to stay, and tourist information, use the Foz do Iguacu travel route planning website.

You can drive from Iguazu National Park to Foz do Iguacu in an hour. Alternatively, you can take a bus. May in Foz do Iguacu sees daily highs of °C and lows of °C at night. Finish your sightseeing early on the 16th (Sun) to allow enough time to travel to Rio de Janeiro.

Things to do in Foz do Iguacu

Nature Parks Shopping
Find places to stay May 15 — 16:
Highlights from your plan
Iguazu Falls ©
Iguazu Falls
Museu de Cera Dreamland ©
Museu de Cera Dreamland
Artesanato Chocolate Caseiro Tres Fronteiras ©

3
nights
Rio de Janeiro, Brazil

Rio de Janeiro ©
Bustling with samba music and all-night street parties, no city encapsulates the spirit of Brazil better than Rio de Janeiro.
Rio de Janeiro is known for beaches, nightlife, and museums. Your plan includes some of its best attractions: appreciate the history behind Corcovado - Christ the Redeemer, enjoy the sand and surf at Praia de Ipanema, step into the grandiose world of Ilha Fiscal, and brush up on your military savvy at Museu Historico do Exercito e Forte de Copacabana.

To find photos, ratings, more things to do, and tourist information, read our Rio de Janeiro trip planner.

Traveling by flight from Foz do Iguacu to Rio de Janeiro takes 4 hours. Alternatively, you can drive; or take a bus. Plan for somewhat warmer temperatures traveling from Foz do Iguacu in May, with highs in Rio de Janeiro at °C and lows at °C. Finish your sightseeing early on the 19th (Wed) to allow enough time to travel to Fernando de Noronha.

Things to do in Rio de Janeiro

Parks Beaches Outdoors
Find places to stay May 16 — 19:
Highlights from your plan
Corcovado - Christ the Redeemer ©
Corcovado - Christ the Redeemer
Praia de Ipanema
Praia de Ipanema
Copacabana Beach ©
Copacabana Beach

4
nights
Fernando de Noronha, Brazil

Fernando de Noronha ©
With 21 lush islands scattered among pristine waters in the Atlantic Ocean, a Fernando de Noronha holiday is well worth the effort it takes to get there.
Fernando de Noronha is known for beaches, museums, and wildlife. Your plan includes some of its best attractions: tour the pleasant surroundings at Baia do Sancho, kick back and relax at Atalaia Beach, get outside with Baia dos Porcos, and indulge in some personalized pampering at some of the best spas.

Planning Fernando de Noronha trip won't be overwheling when you use's Insprock itinerary maker.

You can fly from Rio de Janeiro to Fernando de Noronha in 7.5 hours. The time zone changes from Brasilia Standard Time (BRT) to Fernando de Noronha Standard Time (FNT), which is usually a 1 hour difference. Traveling from Rio de Janeiro in May, expect somewhat warmer with lows of °C in Fernando de Noronha. Finish up your sightseeing early on the 23rd (Sun) so you can travel back home.

Things to do in Fernando de Noronha

Outdoors Beaches Parks
Find places to stay May 19 — 23:
Highlights from your plan
Baia do Sancho ©
Baia do Sancho
Praia do Sueste ©
Praia do Sueste
Baia dos Porcos ©
Baia dos Porcos

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