31 days in Central America & South America Itinerary

31 days in Central America & South America Itinerary

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Route & dates

31 days in Central America & South America Itinerary

Start: Cancun, Mexico
Fly:  6​h
1
Panama City, Panama
— 2 nights
Fly:  7​h 30​min
2
Manaus, Brazil
— 1 day
Fly:  6​h 30​min
3
Fortaleza, Brazil
— 1 night
Fly:  4​h 30​min
4
Brasilia, Brazil
— 1 night
Fly:  2​h
5
Rio de Janeiro, Brazil
— 3 nights
Fly:  6​h 45​min
6
Buenos Aires, Argentina
— 3 nights
Fly:  5​h 15​min
7
Ushuaia, Argentina
— 2 nights
Fly:  2​h
8
El Calafate, Argentina
— 2 nights
Fly:  3​h 45​min
9
San Carlos de Bariloche, Argentina
— 2 nights
Fly:  6​h 45​min
10
Mendoza, Argentina
— 2 nights
Fly + Bus:  2​h
11
Santiago, Chile
— 3 nights
Fly:  6​h 30​min
12
La Paz, Bolivia
— 1 night
Fly:  6​h 15​min
13
Lima, Peru
— 1 night
Fly:  3​h 30​min
14
Bogota, Colombia
— 2 nights
Fly:  3​h 30​min
15
Cartagena, Colombia
— 1 night
+4
Fly + Foot + Bus + Foot + Bus:  8​h 30​min
16
Antigua, Guatemala
— 2 nights
+4
Bus + Foot + Bus + Foot + Fly:  6​h 30​min
End: Cancun, Mexico

2
nights
Panama City, Panama

Panama City ©
Arguably the most modern of Central American cities, Panama City boasts a shimmering skyline of glass skyscrapers.
Kick off your visit on the 1st (Wed): snap pictures at Bridge of the Americas. Keep things going the next day: make a trip to Amador Causeway (Calzada de Amador), then make a trip to Panama Canal, and then learn about all things military at Centro de Interpretacion de Ciudad del Saber.

To see traveler tips, where to stay, more things to do, and more tourist information, read Panama City tour itinerary maker tool .

Cancun, Mexico to Panama City is an approximately 6-hour flight. You can also drive. Expect a bit warmer temperatures when traveling from Cancun in January; daily highs in Panama City reach 36°C and lows reach 28°C. Finish your sightseeing early on the 3rd (Fri) so you can travel to Manaus.

Things to do in Panama City

Historic Sites Neighborhoods Parks
Find places to stay Jan 1 — 3:
Highlights from your plan
Panama Canal ©
Panama Canal
Casco Viejo ©
Casco Viejo
Amador Causeway (Calzada de Amador) ©

1
day
Manaus, Brazil

Manaus ©
It's hard not to get excited when planning a trip to Manaus, capital of the state of Amazonas, and the largest city on the mighty Amazon River.
Start off your visit on the 4th (Sat): buy something for everyone on your list at Manauara Shopping and then explore the activities along Meeting of Waters.

Plan my trip to Manaus with suggested itineraries provided by Inspirock.

Traveling by flight from Panama City to Manaus takes 7.5 hours. Due to the time zone difference, you'll lose 1 hour traveling from Panama City to Manaus. In January, plan for daily highs up to 35°C, and evening lows to 28°C. Finish your sightseeing early on the 4th (Sat) to allow enough time to travel to Fortaleza.

Things to do in Manaus

Parks Nature Shopping
Find places to stay Jan 3 — 4:
Highlights from your plan
Meeting of Waters ©
Meeting of Waters
Manauara Shopping ©
Manauara Shopping

1
night
Fortaleza, Brazil

Fortaleza ©
They don't call Fortaleza "Brazilian Miami" for nothing.
Start off your visit on the 5th (Sun): cool off at Beach Park. Get ready for a full day of sightseeing on the next day: see the interesting displays at 10th GAC Cultural Museum, then tour the pleasant surroundings at Praia de Futuro, and then tour the pleasant surroundings at Iracema Beach.

For photos, reviews, and more tourist information, use the Fortaleza online trip itinerary planner .

You can fly from Manaus to Fortaleza in 6.5 hours. Another option is to do a combination of ferry and bus. The time zone changes from Amazon Time to Brasilia Time, which is usually a 1 hour difference. In January, plan for daily highs up to 35°C, and evening lows to 29°C. Wrap up your sightseeing on the 6th (Mon) to allow time to travel to Brasilia.

Things to do in Fortaleza

Beaches Parks Outdoors

Side Trip

Beach Park
Find places to stay Jan 4 — 6:
Highlights from your plan
Praia do Futuro ©
Praia do Futuro
Beach Park ©
Beach Park
Iracema Beach ©
Iracema Beach

1
night
Brasilia, Brazil

Brasilia ©
Although it lacks the cultural flair of Rio de Janeiro and the massive urban sprawl of Sao Paulo, Brasilia holds a fascinating place in the tapestry of Brazil.
On the 7th (Tue), contemplate in the serene atmosphere at Santuario Dom Bosco, get a sense of history and politics at Itamaraty Palace, admire the landmark architecture of Catedral Metropolitana, then take a leisurely stroll along Pontao do Lago Sul, and finally take in the views from JK Bridge.

To see more things to do, where to stay, and other tourist information, go to the Brasilia day trip planner.

You can fly from Fortaleza to Brasilia in 4.5 hours. Other options are to drive; or take a bus. Expect slightly colder evenings in Brasilia when traveling from Fortaleza in January, with lows around 21°C. Finish up your sightseeing early on the 7th (Tue) so you can travel to Rio de Janeiro.

Things to do in Brasilia

Historic Sites
Find places to stay Jan 6 — 7:
Highlights from your plan
Catedral Metropolitana ©
Catedral Metropolitana
Santuario Dom Bosco ©
Santuario Dom Bosco
Itamaraty Palace ©
Itamaraty Palace

3
nights
Rio de Janeiro, Brazil

Rio de Janeiro ©
Bustling with samba music and all-night street parties, no city encapsulates the spirit of Brazil better than Rio de Janeiro.
Rio de Janeiro is known for beaches, nature, parks, museums, and nightlife. Your plan includes some of its best attractions: get great views at Pao de Acucar, tour the pleasant surroundings at Praia de Ipanema, appreciate the history behind Corcovado Christ the Redeemer, and contemplate the long history of Parque Lage.

To find traveler tips, where to stay, more things to do, and other tourist information, read our Rio de Janeiro road trip planning tool .

Traveling by flight from Brasilia to Rio de Janeiro takes 2 hours. Alternatively, you can drive; or take a bus. Expect somewhat warmer temperatures when traveling from Brasilia in January; daily highs in Rio de Janeiro reach 37°C and lows reach 28°C. Finish up your sightseeing early on the 10th (Fri) so you can travel to Buenos Aires.

Things to do in Rio de Janeiro

Parks Beaches Outdoors
Find places to stay Jan 7 — 10:
Highlights from your plan
Corcovado - Christ the Redeemer ©
Corcovado - Christ the Redeemer
Sugarloaf Mountain ©
Sugarloaf Mountain
Copacabana Beach ©
Copacabana Beach

3
nights
Buenos Aires, Argentina

Buenos Aires ©
Cultural capital of South America, Buenos Aires remains one of the largest cities on the continent, serving as a point of departure for exploring the rest of the country.
Buenos Aires is known for nightlife, museums, parks, historic sites, and shopping. Your plan includes some of its best attractions: don't miss a visit to Cemiterio de Recoleta, shop like a local with Puerto Madero, admire the architecture and history at Plaza de Mayo, and look for gifts at El Ateneo Grand Splendid.

For photos and more tourist information, you can read our Buenos Aires driving holiday planner.

You can fly from Rio de Janeiro to Buenos Aires in 7 hours. Other options are to drive; or take a bus. Plan for slightly colder temperatures traveling from Rio de Janeiro in January, with highs in Buenos Aires at 33°C and lows at 24°C. Wrap up your sightseeing on the 13th (Mon) early enough to travel to Ushuaia.

Things to do in Buenos Aires

Historic Sites Neighborhoods Museums
Find places to stay Jan 10 — 13:
Highlights from your plan
Cemiterio de Recoleta ©
Cemiterio de Recoleta
Parque 3 de Febrero ©
Parque 3 de Febrero
Puerto Madero ©
Puerto Madero

2
nights
Ushuaia, Argentina

Ushuaia ©
Often called the "End of the World" because of its position on the southernmost tip of South America, the expanding city of Ushuaia serves as both a busy commercial port and attractive tourist hub.
Start off your visit on the 14th (Tue): don't miss a visit to Les Éclaireurs Lighthouse, explore the activities along Canal Beagle, then see the interesting displays at Museo del Fin del Mundo, and finally examine the collection at Museo Maritimo y del Presidio de Ushuaia. Get ready for a full day of sightseeing on the 15th (Wed): explore the wealth of natural beauty at Tierra del Fuego National Park and then pause for some photo ops at Plaza Malvinas.

To find reviews, more things to do, photos, and more tourist information, use the Ushuaia online trip maker .

You can fly from Buenos Aires to Ushuaia in 5.5 hours. Alternatively, you can do a combination of car and ferry; or take a bus. In January, Ushuaia is cooler than Buenos Aires - with highs of 15°C and lows of 7°C. Wrap up your sightseeing on the 15th (Wed) to allow time to travel to El Calafate.

Things to do in Ushuaia

Parks Nature Museums
Find places to stay Jan 13 — 15:
Highlights from your plan
Tierra del Fuego National Park ©
Tierra del Fuego National Park
Canal Beagle ©
Canal Beagle

2
nights
El Calafate, Argentina

El Calafate ©
El Calafate tourism thrives mostly thanks to the city's proximity to a World Heritage-listed national park, famed for containing over 40 large glaciers.
Start off your visit on the 16th (Thu): explore the wealth of natural beauty at Parque Nacional Los Glaciares. Get ready for a full day of sightseeing on the 17th (Fri): get outside with Enjoy!, stop by Vellon Negro, and then contemplate the waterfront views at Lago Argentino.

For ratings, traveler tips, and more tourist information, read El Calafate trip planner .

Traveling by flight from Ushuaia to El Calafate takes 2 hours. Alternatively, you can do a combination of car and ferry; or take a bus. Traveling from Ushuaia in January, expect somewhat warmer with lows of 15°C in El Calafate. Wrap up your sightseeing on the 17th (Fri) early enough to travel to San Carlos de Bariloche.

Things to do in El Calafate

Parks Nature Outdoors
Find places to stay Jan 15 — 17:
Highlights from your plan
Parque Nacional Los Glaciares ©
Parque Nacional Los Glaciares
Lago Argentino
Lago Argentino
Vellon Negro ©
Vellon Negro

2
nights
San Carlos de Bariloche, Argentina

San Carlos de Bariloche ©
Nestled against the foothills of the Andes, scenic San Carlos de Bariloche hugs the southern shore of Nahuel Huapi Lake and ranks among Argentina's top destinations for active outdoor vacations.
Start off your visit on the 18th (Sat): hike along Circuito Chico, then take in panoramic vistas at Parque Nacional Nahuel Huapi, and then look for gifts at Chocolaterie VanWynsberghe. Here are some ideas for day two: take some stellar pictures from Piedra de Habsburgo and then paddle through the water with a kayaking and canoeing tour.

To see more things to do, reviews, traveler tips, and more tourist information, read our San Carlos de Bariloche vacation maker tool .

You can fly from El Calafate to San Carlos de Bariloche in 4 hours. Alternatively, you can take a bus; or drive. When traveling from El Calafate in January, plan for somewhat warmer days in San Carlos de Bariloche, with highs around 28°C, while nights are little chillier with lows around 9°C. Finish your sightseeing early on the 19th (Sun) so you can travel to Mendoza.

Things to do in San Carlos de Bariloche

Outdoors Parks Adventure
Find places to stay Jan 17 — 19:
Highlights from your plan
Circuito Chico ©
Circuito Chico
Parque Nacional Nahuel Huapi ©
Parque Nacional Nahuel Huapi
Kayaking & Canoeing

2
nights
Mendoza, Argentina

Famed for its neat vineyards and thriving wine production, Mendoza remains the place to visit for a pleasant combination of relaxation and recreation.
Kick off your visit on the 20th (Mon): do a tasting at Cepas Winery, indulge in some culinary diversions at a local gastronomic tour, then do a tasting at Bodega Roberto Bonfanti, and finally stroll around Parque General San Martin. Keep things going the next day: don't miss a visit to Plaza Independencia, then savor the flavors at Food & Drink, and then take an in-depth tour of Museo Fundacional.

For maps, photos, where to stay, and more tourist information, read our Mendoza itinerary planner .

Fly from San Carlos de Bariloche to Mendoza in 7 hours. Alternatively, you can drive; or take a bus. Expect a bit warmer weather when traveling from San Carlos de Bariloche in January: highs in Mendoza hover around 38°C, while lows dip to 23°C. Finish your sightseeing early on the 21st (Tue) to allow enough time to travel to Santiago.

Things to do in Mendoza

Tours Wineries Museums
Find places to stay Jan 19 — 21:
Highlights from your plan
Food Tours
Parque General San Martin ©
Parque General San Martin
Wine Tours & Tastings

3
nights
Santiago, Chile

Santiago ©
Santiago tourism thrives largely thanks to the city's big selection of cultural and entertainment options, including museums, theaters, restaurants, bars, and giant malls.
Santiago is known for shopping, museums, parks, nature, and historic sites. Your plan includes some of its best attractions: take in the awesome beauty at San Cristóbal Hill, wander the streets of Barrio Bellavista, see the interesting displays at La Chascona, and don't miss a visit to Patio Bellavista.

To see traveler tips, maps, photos, and more tourist information, read our Santiago trip itinerary planning app .

Do a combination of flight and bus from Mendoza to Santiago in 2 hours. Alternatively, you can drive; or take a bus. The time zone difference moving from Argentine Time (ART) to Chile Time (CLT) is minus 1 hour. Finish your sightseeing early on the 24th (Fri) to allow enough time to travel to La Paz.

Things to do in Santiago

Parks Shopping Nature
Find places to stay Jan 21 — 24:
Highlights from your plan
San Cristóbal Hill ©
San Cristóbal Hill
Cerro Santa Lucia ©
Cerro Santa Lucia
La Chascona ©
La Chascona

1
night
La Paz, Bolivia

La Paz ©
Take a moment to catch your breath as you commence your holiday in La Paz.
On the 25th (Sat), make a trip to Mercado de Las Brujas, then enjoy some diversion at Urban Rush Bolivia, and then explore the ancient world of Tiwanaku.

To find more things to do, ratings, where to stay, and tourist information, read our La Paz trip itinerary builder .

Fly from Santiago to La Paz in 6.5 hours. Alternatively, you can drive; or do a combination of bus, car, and train. January in La Paz sees daily highs of 17°C and lows of 4°C at night. Wrap up your sightseeing on the 25th (Sat) early enough to travel to Lima.

Things to do in La Paz

Historic Sites Fun & Games
Find places to stay Jan 24 — 25:
Highlights from your plan
Tiwanaku ©
Tiwanaku
Mercado de Las Brujas ©
Mercado de Las Brujas
Urban Rush Bolivia ©
Urban Rush Bolivia

1
night
Lima, Peru

Lima ©
Founded in 1535 by Spanish explorer Francisco Pizarro, Lima represents an interesting blend of modern attractions and preserved colonial architecture, much of it clustered in the World Heritage-listed city center.
Start off your visit on the 26th (Sun): take an in-depth tour of Museo Larco, view the masterpieces at Galeria Indigo, then make a trip to Miraflores, then walk around Circuito Magico Del Agua, and finally make a trip to Plaza de Armas (Plaza Mayor).

To see where to stay, more things to do, other places to visit, and more tourist information, refer to the Lima online journey maker .

Traveling by flight from La Paz to Lima takes 6.5 hours. Alternatively, you can drive; or take a bus. The time zone difference moving from Bolivia Time (BOT) to Peru Time (PET) is minus 1 hour. Plan for warmer temperatures traveling from La Paz in January, with highs in Lima at 31°C and lows at 24°C. Finish up your sightseeing early on the 26th (Sun) so you can travel to Bogota.

Things to do in Lima

Museums Parks Neighborhoods
Find places to stay Jan 25 — 26:
Highlights from your plan
Museo Larco ©
Museo Larco
Circuito Magico Del Agua ©
Circuito Magico Del Agua
Plaza de Armas (Plaza Mayor) ©
Plaza de Armas (Plaza Mayor)

2
nights
Bogota, Colombia

Bogota ©
Colombia's heart and soul, Bogota has earned the nickname "Athens of South America" thanks to its abundance of universities, libraries, and lower-level schools.
Start off your visit on the 27th (Mon): pause for some serene contemplation at Catedral de Sal de Zipaquira, then explore the world behind art at Museo Botero del Banco de la Republica, and then look for gifts at Vitrina Guayca. On the 28th (Tue), you'll have a packed day of sightseeing: take in the awesome beauty at Monserrate, see the interesting displays at Gold Museum (Museo del Oro), and then contemplate the long history of Bolivar plaza.

Discover how to plan a Bogota trip in just a few steps with Inspirock's itinerary builder.

Getting from Lima to Bogota by flight takes about 3.5 hours. Other options: drive; or take a bus. Expect little chillier weather when traveling from Lima in January: highs in Bogota hover around 23°C, while lows dip to 7°C. Finish your sightseeing early on the 28th (Tue) to allow enough time to travel to Cartagena.

Things to do in Bogota

Museums Historic Sites Parks

Side Trip

Catedral de Sal de Zipaquira
Find places to stay Jan 26 — 28:
Highlights from your plan
Gold Museum (Museo del Oro) ©
Gold Museum (Museo del Oro)
Monserrate ©
Monserrate
Museo Botero del Banco de la Republica ©

1
night
Cartagena, Colombia

Cartagena ©
The site of the continent's first Spanish colony, Cartagena retains much of its colonial flavor thanks to a World Heritage-listed old town, encircled by old walls and protected by imposing fortresses.
On the 29th (Wed), steep yourself in history at Plaza Santo Domingo, contemplate the long history of Torre del Reloj, and then make a trip to Castillo de San Felipe de Barajas.

To find photos, other places to visit, reviews, and other tourist information, read our Cartagena online travel route planner .

You can fly from Bogota to Cartagena in 3.5 hours. Alternatively, you can do a combination of flight and bus; or drive. While traveling from Bogota, expect a bit warmer days and much warmer nights in Cartagena, ranging from highs of 36°C to lows of 28°C. Cap off your sightseeing on the 29th (Wed) early enough to travel to Antigua.

Things to do in Cartagena

Historic Sites
Find places to stay Jan 28 — 29:
Highlights from your plan
Castillo de San Felipe de Barajas ©
Castillo de San Felipe de Barajas
Plaza Santo Domingo ©
Plaza Santo Domingo
Torre del Reloj ©
Torre del Reloj

2
nights
Antigua, Guatemala

Antigua ©
The former capital of Guatemala and a World Heritage Site, Antigua retains its colonial charm and remains one of the most visited destinations in the country.
On the 30th (Thu), get impressive views of Volcán Pacaya, look for gifts at Nim Po't Centro de Textiles Tradicionales, and then take in the architecture and atmosphere at Iglesia de La Merced. Get ready for a full day of sightseeing on the 31st (Fri): contemplate the geological forces at Volcan de Agua and then don't miss a visit to Cerro de la Cruz.

For photos, more things to do, maps, and tourist information, read our Antigua vacation maker .

You can fly from Cartagena to Antigua in 8.5 hours. Alternatively, you can do a combination of bus and flight. The time zone difference when traveling from Cartagena to Antigua is minus 1 hour. When traveling from Cartagena in January, plan for a bit cooler days in Antigua, with highs around 27°C, while nights are cooler with lows around 13°C. Cap off your sightseeing on the 31st (Fri) early enough to travel back home.

Things to do in Antigua

Parks Nature Shopping
Find places to stay Jan 29 — 31:
Highlights from your plan
Volcán Pacaya ©
Volcán Pacaya
Iglesia de La Merced ©
Iglesia de La Merced
Cerro de la Cruz ©
Cerro de la Cruz

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