60 days in South America & Central America Itinerary

60 days in South America & Central America Itinerary

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Route & dates

60 days in South America & Central America Itinerary

Start: Brussels, Belgium
Train + Fly:  12 h
1
Cartagena, Colombia
— 3 nights
Fly:  4 h
2
Medellin, Colombia
— 5 nights
Fly:  1 h 15 min
3
Bogota, Colombia
— 5 nights
Fly:  2 h 30 min
4
San Andres Island, Colombia
— 6 nights
Fly:  1 h 45 min
5
Panama City, Panama
— 6 nights
Fly:  2 h 15 min
6
Bocas Town, Panama
— 1 night
Drive:  4 h 45 min
7
Boquete, Panama
— 4 nights
Drive:  4 h 45 min
8
Manuel Antonio, Costa Rica
— 4 nights
Drive:  4 h 15 min
9
La Fortuna de San Carlos, Costa Rica
— 6 nights
Drive:  3 h 30 min
10
Monteverde, Costa Rica
— 5 nights
Drive:  3 h 15 min
11
Tamarindo, Costa Rica
— 5 nights
Drive:  3 h 30 min
12
San Juan del Sur, Nicaragua
— 1 night
Drive:  3 h 15 min
13
Leon, Nicaragua
— 3 nights
Drive:  2 h 15 min
14
Granada, Nicaragua
— 4 nights
Fly + Train:  15 h 30 min
End: Brussels, Belgium

3
nights
Cartagena, Colombia

Cartagena ©
The site of the continent's first Spanish colony, Cartagena retains much of its colonial flavor thanks to a World Heritage-listed old town, encircled by old walls and protected by imposing fortresses.
Step out of Cartagena with an excursion to Playa Blanca in Isla Baru--about 1h 05 min away. There's still lots to do: make a trip to Castillo de San Felipe de Barajas, stop by El Centro Artesano, take in the architecture and atmosphere at Sanctuary of Saint Peter Claver, and contemplate the long history of Plaza Santo Domingo.

To find traveler tips, where to stay, reviews, and tourist information, read our Cartagena road trip planning site .

Brussels, Belgium to Cartagena is an approximately 12-hour combination of train and flight. You can also fly. Traveling from Brussels to Cartagena, you'll gain 6 hours due to the time zone difference. In September, Cartagena is warmer than Brussels - with highs of 38°C and lows of 30°C. Finish up your sightseeing early on the 5th (Sat) so you can travel to Medellin.

Things to do in Cartagena

Historic Sites Outdoors Parks

Side Trip

Playa Blanca
Find places to stay Sep 2 — 5:
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Castillo de San Felipe de Barajas ©
Castillo de San Felipe de Barajas
Walled City of Cartagena ©
Walled City of Cartagena
Speed Boats Tours

5
nights
Medellin, Colombia

Nestled between rising hills in a narrow valley, Medellin serves as an energetic melting pot of people from all socio-economic classes.
Medellin is known for parks, museums, and zoos & aquariums. Your plan includes some of its best attractions: take in the local highlights with Walking tours, have some family-friendly fun at Tejo In Medellin (tour), see Off-Road Tours, and get engrossed in the history at Museo de Antioquia.

For traveler tips, photos, topicsMoreInfo.option.ratings, and other tourist information, read Medellin trip builder site .

Traveling by flight from Cartagena to Medellin takes 4 hours. Alternatively, you can do a combination of bus and flight; or drive. Traveling from Cartagena in September, things will get a bit cooler in Medellin: highs are around 32°C and lows about 20°C. Finish up your sightseeing early on the 10th (Thu) so you can travel to Bogota.

Things to do in Medellin

Tours Parks Outdoors

Side Trip

Envigado
Find places to stay Sep 5 — 10:
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Off-Road Tours
Walking tours
medellin 2000m DESCENT ©
medellin 2000m DESCENT

5
nights
Bogota, Colombia

Colombia's heart and soul, Bogota has earned the nickname "Athens of South America" thanks to its abundance of universities, libraries, and lower-level schools.
Get out of town with these interesting Bogota side-trips: Zipaquira (Catedral de Sal de Zipaquira & Esensal) and Laguna de Guatavita (in Tierra Negra). There's much more to do: see the interesting displays at Gold Museum (Museo del Oro), contemplate the long history of Bolivar plaza, get the lay of the land with Walking tours, and take in the awesome beauty at Monserrate.

To see where to stay, more things to do, other places to visit, and other tourist information, read our Bogota planner.

Getting from Medellin to Bogota by flight takes about 1.5 hours. Other options: do a combination of shuttle and flight; or drive. Expect little chillier temperatures when traveling from Medellin in September; daily highs in Bogota reach 22°C and lows reach 9°C. Wrap up your sightseeing on the 15th (Tue) early enough to travel to San Andres Island.

Things to do in Bogota

Parks Nature Museums

Side Trips

Zipaquira, Laguna de Guatavita
Find places to stay Sep 10 — 15:
Highlights from your plan
Food Tours
Gold Museum (Museo del Oro) ©
Gold Museum (Museo del Oro)
Monserrate ©
Monserrate

6
nights
San Andres Island, Colombia

San Andres Island ©
The coral San Andres Island boasts a rich colonial history, exotic beaches, and a laidback, tropical lifestyle.
San Andres Island is known for nature, wildlife, and beaches. Your plan includes some of its best attractions: step off the mainland to explore Johnny Cay, identify plant and animal life at Cayo El Acuario, enjoy the sand and surf at Playa de San Luis, and tour the pleasant surroundings at Cocoplum Bay.

To find where to stay, reviews, and tourist information, use the San Andres Island trip builder site .

Traveling by flight from Bogota to San Andres Island takes 2.5 hours. Traveling from Bogota in September, expect nights in San Andres Island to be much warmer, around 30°C, while days are a bit warmer, around 36°C. Wrap up your sightseeing on the 21st (Mon) to allow time to travel to Panama City.

Things to do in San Andres Island

Parks Outdoors Beaches
Find places to stay Sep 15 — 21:
Highlights from your plan
Johnny Cay ©
Johnny Cay
La Piscinita ©
La Piscinita
Hoyo Soplador ©
Hoyo Soplador

6
nights
Panama City, Panama

Panama City ©
Arguably the most modern of Central American cities, Panama City boasts a shimmering skyline of glass skyscrapers.
Venture out of the city with trips to Iglesia de San Pedro (in Isla Taboga), Portobelo (Museo de La Real Aduana de Portobelo & Nature & Wildlife Tours) and Asociacion Panamericana para la Conservacion (in Gamboa). There's much more to do: don't miss a visit to Panama Canal, explore the wealth of natural beauty at Metropolitan National Park, get to know the fascinating history of Casco Viejo, and stroll through Punta Culebra Nature Center.

For photos, where to stay, reviews, and other tourist information, read Panama City trip builder tool .

Fly from San Andres Island to Panama City in 2 hours. In September, daytime highs in Panama City are 36°C, while nighttime lows are 28°C. Finish up your sightseeing early on the 27th (Sun) so you can travel to Bocas Town.

Things to do in Panama City

Parks Neighborhoods Historic Sites

Side Trips

Portobelo, Iglesia de San Pedro, Asociacion Panamericana para la Conservacion, Gatun Locks
Find places to stay Sep 21 — 27:
Highlights from your plan
Panama Canal ©
Panama Canal
Casco Viejo ©
Casco Viejo
Amador Causeway (Calzada de Amador) ©
Amador Causeway (Calzada de Amador)

1
night
Bocas Town, Panama

The colorful and relaxed Bocas Town has a welcoming atmosphere, with the modestly sized urban area showcasing typical Caribbean clapboard houses and home to a mixed community from across the world.
Start off your visit on the 28th (Mon): see some colorful creatures with a scuba or snorkeling tour, explore the engaging exhibits at Plastic Bottle Village, and then enjoy the sand and surf at Boca del Drago.

For maps, more things to do, other places to visit, and other tourist information, go to the Bocas Town trip planner.

You can fly from Panama City to Bocas Town in 2.5 hours. Alternatively, you can do a combination of flight, bus, and ferry; or do a combination of bus and ferry. Traveling from Panama City in September, expect somewhat warmer with lows of 34°C in Bocas Town. Finish your sightseeing early on the 28th (Mon) to allow enough time to drive to Boquete.

Things to do in Bocas Town

Outdoors Wildlife Tours
Find places to stay Sep 27 — 28:
Highlights from your plan
Scuba & Snorkeling
Boca del Drago ©
Boca del Drago
Plastic Bottle Village ©
Plastic Bottle Village

4
nights
Boquete, Panama

Boquete ©
Now known internationally for its fresh mountain air, year-round pleasant temperatures, and large community of North American expats, Boquete has changed rapidly since the start of the century, changing from a humble mountain town, into a humble mountain surrounded by gated communities and estates.
Change things up with a short trip to Finca Dracula in Cerro Punta (about 2 hours away). There's lots more to do: stroll through Sendero Los Quetzales (The Quetzales Trail), head off the coast to Cayo Zapatilla, get outside with Finca Lerida Activities, and take in the dramatic natural features at Los Ladrillos.

To see photos, more things to do, other places to visit, and tourist information, you can read our Boquete trip itinerary maker.

You can drive from Bocas Town to Boquete in 5 hours. Wrap up your sightseeing on the 2nd (Fri) to allow time to drive to Manuel Antonio.

Things to do in Boquete

Parks Outdoors Trails

Side Trip

Finca Dracula
Find places to stay Sep 28 — Oct 2:
Highlights from your plan
Finca Dracula ©
Finca Dracula
Volcan Baru National Park ©
Volcan Baru National Park

4
nights
Manuel Antonio, Costa Rica

Manuel Antonio ©
The rainforest meets the sea at Manuel Antonio National Park, a small but scenic natural preserve on the west coast of Costa Rica.
Change things up with these side-trips from Manuel Antonio: Jaco (Mirador de Jaco, Zipline, &more). There's much more to do: stroll through Playa Manuel Antonio, find your balance on the water with categoryPhrases.alias.some_of_the_best_stand_up_paddleboarding_in_the_area, let the river carry you with a rafting and tubing tour, and stroll around Parque Nahomi.

To see other places to visit, traveler tips, more things to do, and tourist information, go to the Manuel Antonio travel planner.

You can drive from Boquete to Manuel Antonio in 5 hours. Other options are to do a combination of car and bus; or take a bus. The time zone difference when traveling from Boquete to Manuel Antonio is minus 1 hour. Cap off your sightseeing on the 6th (Tue) early enough to go by car to La Fortuna de San Carlos.

Things to do in Manuel Antonio

Outdoors Tours Adventure

Side Trips

Jaco, Quepos
Find places to stay Oct 2 — 6:
Highlights from your plan
Playa Manuel Antonio ©
Playa Manuel Antonio
Canyoning & Rappelling Tours
River Rafting & Tubing

6
nights
La Fortuna de San Carlos, Costa Rica

Set against the backdrop of the imposing Arenal Volcano, La Fortuna de San Carlos offers visitors a chance to explore diverse natural landscapes and sample some delicious local produce.
Step out of La Fortuna de San Carlos with an excursion to Poas Volcano in Poas Volcano National Park--about 1h 55 min away. Next up on the itinerary: take in the natural beauty of Tabacon Hot Springs, head outdoors with Salto, tour the pleasant surroundings at Proyecto Asis, and relax in the rural setting at Finca Luna Nueva.

Find out how to plan La Fortuna de San Carlos trip without stress by asking Inspirock to help create an itinerary.

You can drive from Manuel Antonio to La Fortuna de San Carlos in 4.5 hours. Alternatively, you can take a shuttle; or take a bus. Cap off your sightseeing on the 12th (Mon) early enough to go by car to Monteverde.

Things to do in La Fortuna de San Carlos

Parks Nature Spas

Side Trips

Arenal Volcano National Park, Finca Luna Nueva, Poas Volcano
Find places to stay Oct 6 — 12:
Highlights from your plan
River Rafting & Tubing
Tabacon Hot Springs ©
Tabacon Hot Springs
Arenal Volcano
Arenal Volcano

5
nights
Monteverde, Costa Rica

Monteverde ©
Monteverde is all about natural attractions, not surprising for an eco-tourism hotspot known for its cloud forests and rich diversity of animal life.
Change things up with a short trip to Piedra de Fuego in Esparza (about 1h 30 min away). The adventure continues: tour the pleasant surroundings at Monteverde Cloud Forest Biological Reserve, experience rural life at Hidden Valley Permaculture Farm, admire the natural beauty at Monteverde Orchid Garden, and ride a horse along Finca el Rodeo.

To find reviews, other places to visit, and tourist information, read Monteverde trip maker app .

Traveling by car from La Fortuna de San Carlos to Monteverde takes 3.5 hours. Alternatively, you can take a shuttle. Finish up your sightseeing early on the 17th (Sat) so you can go by car to Tamarindo.

Things to do in Monteverde

Parks Wildlife Outdoors

Side Trip

Piedra de Fuego
Find places to stay Oct 12 — 17:
Highlights from your plan
Zipline
El Trapiche Tour ©
El Trapiche Tour

5
nights
Tamarindo, Costa Rica

Tamarindo ©
Surfing remains the main reason to take a trip to Tamarindo, as the beachside town is mostly known for its excellent waves.
Explore Tamarindo's surroundings by going to SIBU Wildlife Sanctuary (in Nosara), Area de Conservacion Guanacaste (Hacienda El Viejo Wetlands & Four Seasons Golf Club) and Garra de Leon Golf Course (in Playa Conchal). There's lots more to do: get a taste of life in the country at Pura Aventura, tee off at TurfSafari, see majestic marine mammals with a dolphin and whale watching tour, and kick back and relax at Tamarindo Beach.

For photos, topicsMoreInfo.option.ratings, more things to do, and more tourist information, you can read our Tamarindo trip planner.

Drive from Monteverde to Tamarindo in 3.5 hours. Alternatively, you can take a shuttle; or take a bus. Finish your sightseeing early on the 22nd (Thu) to allow enough time to drive to San Juan del Sur.

Things to do in Tamarindo

Outdoors Parks Wildlife

Side Trips

Area de Conservacion Guanacaste, Playa Nacascolo, Black Stallion Eco Park & Estates, Dolphin & Whale Watching, Garra de Leon Golf Course
Find places to stay Oct 17 — 22:
Highlights from your plan
Pura Aventura ©
Pura Aventura
Hacienda El Viejo Wetlands ©
Hacienda El Viejo Wetlands
Dolphin & Whale Watching

1
night
San Juan del Sur, Nicaragua

San Juan del Sur ©
Set in a crescent-shaped bay, San Juan del Sur has become known as a popular surfing spot and coastal holiday destination for Nicaraguan families and international visitors alike.
Start off your visit on the 23rd (Fri): get your game on at Surf Ranch Skateboard Park, then identify plant and animal life at La Flor Beach Natural Reserve, and then don't miss a visit to Mirador del Cristo de la Misericordia.

For more things to do, traveler tips, topicsMoreInfo.option.ratings, and other tourist information, go to the San Juan del Sur sightseeing planning tool .

Getting from Tamarindo to San Juan del Sur by car takes about 3.5 hours. Other options: do a combination of bus and car; or do a combination of bus and shuttle. In October, plan for daily highs up to 35°C, and evening lows to 28°C. Cap off your sightseeing on the 23rd (Fri) early enough to go by car to Leon.

Things to do in San Juan del Sur

Outdoors Parks Wildlife
Find places to stay Oct 22 — 23:
Highlights from your plan
La Flor Beach Natural Reserve ©
La Flor Beach Natural Reserve
Mirador del Cristo de la Misericordia ©

3
nights
Leon, Nicaragua

Leon ©
A cultured and storied city, Leon attracts guests from all over the world, drawn to the second city's style, thriving intellectual life, and liveliness.
When in Leon, make a side trip to see Juan Venado Island Nature Reserve in Las Penitas, approximately Las Penitas away. There's lots more to do: contemplate the geological forces at Cerro Negro Volcano, contemplate the long history of Iglesia San Juan Bautista de Subtiava, stop by Catedral de la Asunción, and see Off-Road Tours.

To find reviews, where to stay, and more tourist information, refer to the Leon trip itinerary maker.

You can drive from San Juan del Sur to Leon in 3.5 hours. Other options are to take a shuttle; or take a bus. In October in Leon, expect temperatures between 36°C during the day and 28°C at night. Wrap up your sightseeing on the 26th (Mon) to allow time to drive to Granada.

Things to do in Leon

Parks Nature Outdoors

Side Trip

Juan Venado Island Nature Reserve
Find places to stay Oct 23 — 26:
Highlights from your plan
Cerro Negro Volcano ©
Cerro Negro Volcano
Catedral de la Asunción ©
Catedral de la Asunción
Momotombo ©
Momotombo

4
nights
Granada, Nicaragua

Granada ©
The lakeside city of Granada has the look and feel of a historically important economic and political center, with grand colonial architecture, a unified look, and many cultural attractions.
Explore the numerous day-trip ideas around Granada: Santiago of Managua Cathedral (in Managua), Masaya Volcano (in Masaya) and Apoyo (in La Laguna de Apoyo). And it doesn't end there: take in the architecture and atmosphere at Iglesia de La Merced, examine the collection at Centro Cultural Antiguo Convento San Francisco, explore the world behind art at Casa de Los Tres Mundos, and delve into the lush surroundings at Mombacho Volcano National Preserve.

For topicsMoreInfo.option.ratings, where to stay, traveler tips, and other tourist information, go to the Granada trip itinerary maker website .

Traveling by car from Leon to Granada takes 2.5 hours. Alternatively, you can take a shuttle; or take a bus. Finish up your sightseeing early on the 30th (Fri) so you can travel back home.

Things to do in Granada

Parks Nature Museums

Side Trips

Masaya, Santiago of Managua Cathedral
Find places to stay Oct 26 — 30:
Highlights from your plan
Islets of Granada ©
Islets of Granada
Iglesia de La Merced ©
Iglesia de La Merced
Masaya Volcano ©
Masaya Volcano

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