60 days in South America, Caribbean, Central America & Mexico Itinerary

60 days in South America, Caribbean, Central America & Mexico Itinerary

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60 days in South America, Caribbean, Central America & Mexico Itinerary

Start: Lisbon, Portugal
Fly + Shuttle:  17 h
1
Buenos Aires, Argentina
— 3 nights
Fly + Bus:  5 h 30 min
2
San Carlos de Bariloche, Argentina
— 7 nights
Fly + Taxi:  18 h 30 min
3
Uyuni, Bolivia
— 2 nights
Taxi + Fly:  11 h
4
Cusco, Peru
— 5 nights
Fly + Drive:  10 h 30 min
5
San Andres, Colombia
— 4 nights
Drive + Fly:  4 h
6
Cartagena, Colombia
— 6 nights
Fly:  7 h 30 min
7
Havana, Cuba
— 6 nights
Drive:  2 h
8
Varadero, Cuba
— 5 nights
+10
Bus + Foot + Train + Foot + Bus + Taxi + Fly + Foot + Bus + Foot + Bus:  8 h
9
Antigua, Guatemala
— 1 night
+7
Bus + Foot + Bus + Foot + Fly + Shuttle + Foot + Bus:  9 h 30 min
10
San Juan del Sur, Nicaragua
— 4 nights
Drive + Fly:  10 h 30 min
11
Mexico City, Mexico
— 4 nights
Fly:  6 h 30 min
12
Playa del Carmen, Mexico
— 10 nights
+2
Bus + Foot + Fly:  13 h
End: Lisbon, Portugal

3
nights
Buenos Aires, Argentina

Buenos Aires ©
Cultural capital of South America, Buenos Aires remains one of the largest cities on the continent, serving as a point of departure for exploring the rest of the country.
On the 20th (Wed), don't miss a visit to Recoleta Cemetery, explore the world behind art at Museo Nacional de Bellas Artes, and then take in nature's colorful creations at Parque 3 de Febrero. Keep things going the next day: take in the history at Plaza de Mayo, wander the streets of Puerto Madero, and then explore the world behind art at Museum of Latin American Art of Buenos Aires.

To see traveler tips, other places to visit, and other tourist information, you can read our Buenos Aires travel route planner .

Lisbon, Portugal to Buenos Aires is an approximately 17-hour flight. You can also do a combination of flight and bus; or do a combination of flight and ferry. You'll gain 3 hours traveling from Lisbon to Buenos Aires due to the time zone difference. In March, Buenos Aires is somewhat warmer than Lisbon - with highs of 29°C and lows of 20°C. Finish up your sightseeing early on the 22nd (Fri) so you can travel to San Carlos de Bariloche.

Things to do in Buenos Aires

Museums Historic Sites Parks
Find places to stay Mar 19 — 22:
Highlights from your plan
Cemiterio de Recoleta ©
Cemiterio de Recoleta
Parque 3 de Febrero ©
Parque 3 de Febrero

7
nights
San Carlos de Bariloche, Argentina

Nestled against the foothills of the Andes, scenic San Carlos de Bariloche hugs the southern shore of Nahuel Huapi Lake and ranks among Argentina's top destinations for active outdoor vacations.
Get in touch with nature at Nature & Wildlife Tours and Parque Nacional Nahuel Huapi. Satisfy your inner culture vulture at Catedral de San Carlos de Bariloche and Museo del Lago Gutierrez. There's still lots to do: head off the coast to Isla Victoria, get outside with Outdoor Activities, pause for some photo ops at Centro Civico, and let the river carry you with a rafting and tubing tour.

For where to stay, other places to visit, and tourist information, use the San Carlos de Bariloche driving holiday planner.

You can fly from Buenos Aires to San Carlos de Bariloche in 5.5 hours. Other options are to do a combination of train and flight; or drive. Expect a bit cooler weather when traveling from Buenos Aires in March: highs in San Carlos de Bariloche hover around 23°C, while lows dip to 5°C. Finish up your sightseeing early on the 29th (Fri) so you can travel to Uyuni.

Things to do in San Carlos de Bariloche

Outdoors Parks Nature
Find places to stay Mar 22 — 29:
Highlights from your plan
Nature & Wildlife Tours
Parque Nacional Nahuel Huapi ©
Parque Nacional Nahuel Huapi
Ventisquero Negro ©
Ventisquero Negro

2
nights
Uyuni, Bolivia

Uyuni ©
Emptiness surrounds the desert outpost of Uyuni, the gateway to the world's largest salt flats.
Kick off your visit on the 30th (Sat): head off the coast to Isla Incahuasi and then take in the dramatic natural features at Salar de Uyuni. On the 31st (Sun), you'll have a packed day of sightseeing: contemplate the geological forces at Tunupa Volcano.

For maps, where to stay, photos, and tourist information, you can read our Uyuni road trip website .

Do a combination of flight and taxi from San Carlos de Bariloche to Uyuni in 20 hours. Alternatively, you can drive; or do a combination of bus, car, train, and taxi. You'll gain 1 hour traveling from San Carlos de Bariloche to Uyuni due to the time zone difference. Traveling from San Carlos de Bariloche in March, you will find days in Uyuni are a bit cooler (11°C), and nights are somewhat warmer (9°C). Finish up your sightseeing early on the 1st (Mon) so you can travel to Cusco.

Things to do in Uyuni

Parks Nature
Find places to stay Mar 29 — Apr 1:
Highlights from your plan
Salar de Uyuni ©
Salar de Uyuni
Isla Incahuasi ©
Isla Incahuasi
Tunupa Volcano ©
Tunupa Volcano

5
nights
Cusco, Peru

Cusco ©
Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.
Visit Sacsayhuaman and Plaza de Armas for their historical value. Escape the urban bustle at River Rafting & Tubing and Salinas de Maras. Next up on the itinerary: contemplate the long history of Sacred Valley of the Incas, appreciate the extensive heritage of San Blas, and explore the ancient world of Tipon.

For more things to do, other places to visit, photos, and tourist information, use the Cusco travel planner .

Traveling by combination of car and flight from Uyuni to Cusco takes 8.5 hours. Alternatively, you can drive; or do a combination of car and bus. You'll gain 1 hour traveling from Uyuni to Cusco due to the time zone difference. While traveling from Uyuni, expect a bit warmer days and about the same nights in Cusco, ranging from highs of 23°C to lows of 7°C. Wrap up your sightseeing on the 6th (Sat) to allow time to travel to San Andres.

Things to do in Cusco

Historic Sites Tours Adventure

Side Trips

Sacred Valley of the Incas, Salinas de Maras
Find places to stay Apr 1 — 6:
Highlights from your plan
Sacsayhuaman ©
Sacsayhuaman
Sacred Valley of the Incas ©
Sacred Valley of the Incas
River Rafting & Tubing

4
nights
San Andres, Colombia

San Andres
If you're looking for sunshine, clear waters, and tropical warmth, a San Andres vacation could be just what the doctor ordered.
Take a break from the city and head to Playa de San Luis and Cayo Bolivar. You'll discover tucked-away gems like West View and Morgan's Cave. It doesn't end there: kick back and relax at Playa de Spratt Bight.

To see more things to do, photos, ratings, and tourist information, go to the San Andres tour planning website .

The Route module can help you plan travel from Cusco to San Andres. While traveling from Cusco, expect a bit warmer days and warmer nights in San Andres, ranging from highs of 36°C to lows of 30°C. Wrap up your sightseeing by early afternoon on the 10th (Wed) to allow time for travel to Cartagena.

Things to do in San Andres

Parks Beaches Nature

Side Trip

San Andres Island
Find places to stay Apr 6 — 10:
Highlights from your plan
West View
West View
Playa de Spratt Bight ©
Playa de Spratt Bight
Cayo Bolivar ©
Cayo Bolivar

6
nights
Cartagena, Colombia

Cartagena ©
The site of the continent's first Spanish colony, Cartagena retains much of its colonial flavor thanks to a World Heritage-listed old town, encircled by old walls and protected by imposing fortresses.
Do some cultural sightseeing at Plaza Santo Domingo and Sanctuary of Saint Peter Claver. Deepen your sense of the past at sights like Walled City of Cartagena and Torre del Reloj. When in Cartagena, make a side trip to see Playa Blanca in Isla Baru, approximately 1h 05 min away. Spend the 14th (Sun) among aquatic life with a scuba or snorkeling tour. The adventure continues: contemplate in the serene atmosphere at Convent of Santa Cruz de la Popa, get engrossed in the history at Museo del Oro Zenu, explore the historical opulence of San Felipe de Barajas Castle, and make a trip to Plaza Bolivar.

To find more things to do, traveler tips, and other tourist information, read our Cartagena journey builder tool .

Explore your travel options from San Andres to Cartagena with the Route module. In April, daily temperatures in Cartagena can reach 38°C, while at night they dip to 30°C. Wrap up your sightseeing on the 16th (Tue) early enough to travel to Havana.

Things to do in Cartagena

Historic Sites Outdoors Tours

Side Trip

Playa Blanca
Find places to stay Apr 10 — 16:
Highlights from your plan
Torre del Reloj ©
Torre del Reloj
Scuba & Snorkeling
Plaza Santo Domingo ©
Plaza Santo Domingo

6
nights
Havana, Cuba

Havana ©
Cuba's capital and major commercial center, Havana manages to be very old and very modern at the same time.
Do some cultural sightseeing at Old Havana and El Morro. Discover out-of-the-way places like Playas de Este and Havana Cathedral. Go for a jaunt from Havana to Santa Cruz del Norte to see Playa de Jibacoa about 1h 10 min away. There's still lots to do: get to know the fascinating history of El Malecon, don't miss a visit to Plaza de Armas, contemplate the long history of Castillo de San Carlos de la Cabana, and explore the different monuments and memorials at Christopher Columbus Cemetery (Cemetario de Colon).

To see traveler tips, photos, where to stay, and tourist information, you can read our Havana vacation website .

Fly from Cartagena to Havana in 8.5 hours. Alternatively, you can do a combination of bus and flight. Traveling from Cartagena in April, expect slightly colder with lows of 22°C in Havana. Wrap up your sightseeing on the 22nd (Mon) early enough to drive to Varadero.

Things to do in Havana

Historic Sites Beaches Parks

Side Trip

Playa de Jibacoa
Find places to stay Apr 16 — 22:
Highlights from your plan
Old Havana ©
Old Havana
Finca Vigía ©
Finca Vigía
El Morro ©
El Morro

5
nights
Varadero, Cuba

Varadero ©
One of the largest resort towns in the Caribbean, Varadero boasts a 20 km (12 mi) long stretch of sand, lined with hotels and all-inclusive resorts.
You'll enjoy a bit of beach vacationing at Varadero Beach and Cayo Blanco. Eschew the tourist crowds and head to Saturno Cave and Varahicacos Ecological Reserve. Change things up with a short trip to Parque de la Libertad in Matanzas (about 54 minutes away). There's much more to do: stroll through Coral Beach, steep yourself in history at Ambrosio Cave, admire nature's wide array of creatures at Delfinario, and tee off at Varadero Golf Club.

To find where to stay, reviews, photos, and tourist information, refer to the Varadero trip planner .

Drive from Havana to Varadero in 2 hours. Alternatively, you can do a combination of train and taxi; or take a bus. In April, daily temperatures in Varadero can reach 36°C, while at night they dip to 22°C. Wrap up your sightseeing on the 27th (Sat) early enough to travel to Antigua.

Things to do in Varadero

Parks Outdoors Beaches

Side Trip

Matanzas
Find places to stay Apr 22 — 27:
Highlights from your plan
Varadero Beach ©
Varadero Beach
Cayos Blancos ©
Cayos Blancos
Coral Beach - Playa Coral ©
Coral Beach - Playa Coral

1
night
Antigua, Guatemala

Antigua ©
The former capital of Guatemala and a World Heritage Site, Antigua retains its colonial charm and remains one of the most visited destinations in the country.
For other places to visit, reviews, more things to do, and tourist information, use the Antigua online tour planner .

Traveling by combination of flight and shuttle from Varadero to Antigua takes 5.5 hours. Alternatively, you can do a combination of bus, flight, and shuttle. You'll gain 1 hour traveling from Varadero to Antigua due to the time zone difference. Prepare for little chillier weather when traveling from Varadero in April: high temperatures in Antigua hover around 32°C and lows are around 17°C. Cap off your sightseeing on the 28th (Sun) early enough to travel to San Juan del Sur.

Things to do in Antigua

Historic Sites
Find places to stay Apr 27 — 28:
Highlights from your plan
Convento de las Capuchinas ©
Convento de las Capuchinas

4
nights
San Juan del Sur, Nicaragua

San Juan del Sur ©
Set in a crescent-shaped bay, San Juan del Sur has become known as a popular surfing spot and coastal holiday destination for Nicaraguan families and international visitors alike.
You'll discover tucked-away gems like San Juan del Sur Beach and Da' Flying Frog Extreme Adventure. Visit La Flor Beach Natural Reserve and Playa Hermosa for some beach relaxation.

To see ratings, other places to visit, more things to do, and more tourist information, refer to the San Juan del Sur trip planning site .

Traveling by combination of shuttle and flight from Antigua to San Juan del Sur takes 9.5 hours. Alternatively, you can drive; or do a combination of shuttle, flight, and bus. While traveling from Antigua, expect a bit warmer days and much hotter nights in San Juan del Sur, ranging from highs of 38°C to lows of 30°C. Finish your sightseeing early on the 2nd (Thu) so you can travel to Mexico City.

Things to do in San Juan del Sur

Outdoors Beaches Parks
Find places to stay Apr 28 — May 2:
Highlights from your plan
San Juan del Sur Beach ©
San Juan del Sur Beach
La Flor Beach Natural Reserve ©
La Flor Beach Natural Reserve
Playa Hermosa ©
Playa Hermosa

4
nights
Mexico City, Mexico

Mexico City ©
Breathtakingly large, Mexico City provides a home for almost 9 million people living in nearly 1,700 distinct neighborhoods.
Your cultural itinerary includes sights like National Museum of Anthropology (Museo Nacional de Antropologia) and Metropolitan Cathedral (Catedral Metropolitana). Museo del Templo Mayor and Zocalo will appeal to history buffs. Go for a jaunt from Mexico City to Sian Ka'an to see Sian Ka'an Biosphere Reserve about 42 minutes away. The adventure continues: admire the masterpieces at Palacio de Bellas Artes, ponder the world of politics at National Palace (Palacio Nacional), and see the interesting displays at Frida Kahlo Museum.

For traveler tips, photos, more things to do, and other tourist information, read our Mexico City trip itinerary planner.

Use the Route module to find suitable travel options from San Juan del Sur to Mexico City. Traveling from San Juan del Sur in May, expect nights in Mexico City to be colder, around 16°C, while days are slightly colder, around 30°C. Cap off your sightseeing on the 6th (Mon) early enough to travel to Playa del Carmen.

Things to do in Mexico City

Museums Historic Sites Parks

Side Trip

Sian Ka'an Biosphere Reserve
Find places to stay May 2 — 6:
Highlights from your plan
Museo Nacional de Antropologia ©
Museo Nacional de Antropologia
Museo del Templo Mayor ©
Museo del Templo Mayor

10
nights
Playa del Carmen, Mexico

Playa del Carmen ©
The tourist hub of the popular Mayan Riviera, upscale Playa del Carmen remains the jewel of Mexico's Caribbean coastline.
Escape the urban bustle at Palancar Reef and Xel-Ha. Explore hidden gems such as Paradise Beach and Yal-ku Lagoon. Venture out of the city with trips to Tulum (Grand Cenote & Ruins of Tulum), Cozumel (Scuba & Snorkeling, Fishing Charters & Tours, & more) and Cobá Zona Arqueológica Cobá (in Coba). Next up on the itinerary: cool off at Xcaret Park, get close to the beloved marine mammals with a swim-with-the-dolphins experience, and take in the architecture and atmosphere at Nuestra Senora del Carmen Catholic Church.

To see photos, more things to do, maps, and more tourist information, go to the Playa del Carmen online travel planner .

Do a combination of flight and bus from Mexico City to Playa del Carmen in 5.5 hours. Alternatively, you can do a combination of bus and flight; or drive. The time zone difference when traveling from Mexico City to Playa del Carmen is 1 hour. Prepare for a bit warmer weather when traveling from Mexico City in May: high temperatures in Playa del Carmen hover around 34°C and lows are around 25°C. Finish your sightseeing early on the 16th (Thu) so you can travel back home.

Things to do in Playa del Carmen

Outdoors Wildlife Tours

Side Trips

Cozumel, Tulum, Cobá Zona Arqueológica Cobá, Xel-Ha Park by Xcaret, Yal-ku Lagoon
Find places to stay May 6 — 16:
Highlights from your plan
Tulum Archaeological Site ©
Tulum Archaeological Site
Palancar Reef ©
Palancar Reef
Xel-Ha Park by Xcaret ©
Xel-Ha Park by Xcaret

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