44 days in Mexico, Central America & South America Itinerary

44 days in Mexico, Central America & South America Itinerary

Make it your trip
Fly
1
Mexico City, Mexico
— 2 nights
Fly
2
Cancun, Mexico
— 3 nights
Drive
3
Tulum, Mexico
— 3 nights
Drive
4
Granada, Nicaragua
— 1 night
Drive
5
San Juan del Sur, Nicaragua
— 3 nights
Drive to Augusto C. Sandino (Managua) International Airport, Fly to Providencia Island
6
Providencia Island, Colombia
— 2 nights
Fly
7
San Jose, Costa Rica
— 3 nights
Drive
8
Puerto Viejo de Talamanca, Costa Rica
— 3 nights
Drive
9
Bocas del Toro, Panama
— 3 nights
Fly
10
Panama City, Panama
— 2 nights
Fly
11
Cartagena, Colombia
— 3 nights
Fly
12
Medellin, Colombia
— 2 nights
Drive
13
Guatape, Colombia
— 2 nights
Drive
14
Lima, Peru
— 2 nights
Fly
15
Machu Picchu, Peru
— 2 nights
Fly

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Mexico City, Mexico — 2 nights

City of Palaces

Breathtakingly large, Mexico City provides a home for almost 9 million people living in nearly 1,700 distinct neighborhoods.
On the 9th (Sun), step into the grandiose world of Chapultepec Castle, then get a sense of history and politics at National Palace, then appreciate the extensive heritage of Zocalo, and finally take in the exciting artwork at Ambarte. Get ready for a full day of sightseeing on the 10th (Mon): contemplate in the serene atmosphere at Metropolitan Cathedral (Catedral Metropolitana) and then steep yourself in history at Basilica de Santa Maria de Guadalupe.

To see maps, where to stay, and other tourist information, refer to the Mexico City trip planner.

Miami, USA to Mexico City is an approximately 6.5-hour flight. You can also drive; or take a bus. You'll gain 1 hour traveling from Miami to Mexico City due to the time zone difference. When traveling from Miami in July, plan for little chillier days in Mexico City, with highs around 27°C, while nights are cooler with lows around 15°C. Cap off your sightseeing on the 10th (Mon) early enough to catch the flight to Cancun.
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Historic Sites · Shopping · Museums
Find places to stay Jul 8 — 10:

Cancun, Mexico — 3 nights

Few destinations in Mexico dazzle visitors quite like Cancun, a modern resort town filled with glitzy hotels sitting on picturesque and well-developed Caribbean beaches.
Kick off your visit on the 11th (Tue): stop by Tattoo Studio Henna, buy something for everyone on your list at La Isla Shopping Village, and then indulge in some personalized pampering at some of the best spas. On the next day, stroll around arte Garden, then don't miss a visit to El Parque de las Palapas, then get a new perspective on things with Boat Tours & Water Sports, and finally hunt for treasures at Mercado 28.

To see photos, other places to visit, where to stay, and tourist information, read Cancun route builder.

Fly from Mexico City to Cancun in 4 hours. Alternatively, you can drive; or take a bus. The time zone difference when traveling from Mexico City to Cancun is 1 hour. Expect a bit warmer temperatures when traveling from Mexico City in July; daily highs in Cancun reach 36°C and lows reach 28°C. Cap off your sightseeing on the 13th (Thu) early enough to go by car to Tulum.
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Shopping · Outdoors · Wildlife · Tours
Find places to stay Jul 10 — 13:

Tulum, Mexico — 3 nights

The only Mayan site built to overlook the ocean, Tulum remains a coastal paradise preserving the last vestiges of a pre-Hispanic civilization.
Change things up with a short trip to Zona Arqueologica de Coba in Coba (about 48 minutes away). Spend the 14th (Fri) among aquatic life with a scuba or snorkeling tour. And it doesn't end there: explore the ancient world of Tulum Archaeological Site, Head underground at Gran Cenote, relax and rejuvenate at some of the best spas, and examine the collection at Mystika Immersive.

For more things to do, reviews, ratings, and other tourist information, refer to the Tulum travel itinerary planner.

Drive from Cancun to Tulum in 2 hours. Alternatively, you can take a shuttle; or take a bus. Expect a daytime high around 35°C in July, and nighttime lows around 26°C. Finish your sightseeing early on the 16th (Sun) so you can drive to Granada.
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Wildlife · Parks · Outdoors · Tours
Side Trip
Find places to stay Jul 13 — 16:

Granada, Nicaragua — 1 night

La Gran Sultana

The lakeside city of Granada has the look and feel of a historically important economic and political center, with grand colonial architecture, a unified look, and many cultural attractions.
On the 18th (Tue), get impressive views of Mombacho, take in the architecture and atmosphere at Iglesia de La Merced, and then take in the exciting artwork at Galeria Mi Camara Mi Mundo.

To find maps, traveler tips, ratings, and tourist information, read our Granada road trip app.

Traveling by car from Tulum to Granada takes 25 hours. The time zone changes from Eastern Standard Time to Central Standard Time, which is usually a -1 hour difference. Cap off your sightseeing on the 18th (Tue) early enough to go by car to San Juan del Sur.
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Parks · Nature · Historic Sites · Shopping
Find places to stay Jul 17 — 18:

San Juan del Sur, Nicaragua — 3 nights

Set in a crescent-shaped bay, San Juan del Sur has become known as a popular surfing spot and coastal holiday destination for Nicaraguan families and international visitors alike.
San Juan del Sur is known for adventure, beaches, and sightseeing. Your trip includes some of its best attractions: kick back and relax at La Flor Beach Natural Reserve, don't miss a visit to Mirador del Cristo de la Misericordia, relax and rejuvenate at Pranamaya Yoga & Thai Massage Studio Playa Maderas, and head outdoors with Da' Flying Frog Extreme Adventure.

To see other places to visit, more things to do, reviews, and other tourist information, use the San Juan del Sur trip itinerary tool.

You can drive from Granada to San Juan del Sur in 2 hours. Other options are to do a combination of shuttle and bus; or take a bus. In July in San Juan del Sur, expect temperatures between 35°C during the day and 30°C at night. Finish up your sightseeing early on the 21st (Fri) so you can travel to Providencia Island.
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Outdoors · Parks · Beaches · Wildlife
Find places to stay Jul 18 — 21:

Providencia Island, Colombia — 2 nights

Although part of Colombia, the small, isolated Providencia Island retains its Caribbean culture and English-Creole language.
On the 22nd (Sat), take in the dramatic natural features at Morgan's Head. On the next day, step off the mainland to explore Crab Cay-Cayo Cangrejo and then see some colorful creatures with a scuba or snorkeling tour.

To find ratings, where to stay, other places to visit, and more tourist information, refer to the Providencia Island travel route planner.

Explore your travel options from San Juan del Sur to Providencia Island with the Route module. Due to the time zone difference, you'll lose 1 hour traveling from San Juan del Sur to Providencia Island. In July, daily temperatures in Providencia Island can reach 36°C, while at night they dip to 31°C. Finish up your sightseeing early on the 24th (Mon) so you can travel to San Jose.
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Parks · Nature · Outdoors · Wildlife
Find places to stay Jul 22 — 24:

San Jose, Costa Rica — 3 nights

A trip to San Jose, the capital, commercial center, and cultural hub of Costa Rica, gives you a chance to experience the lively atmosphere and rich cultural past of this vibrant country.
When in San Jose, make a side trip to see Jardins da Cachoeira de La Paz in Vara Blanca, approximately Vara Blanca away. Next up on the itinerary: capture your vacation like a pro with an inspiring photography tour, take in the exciting artwork at Galeria Namu, take a tour by water with Boat Tours & Water Sports, and examine the collection at Pre-Columbian Gold Museum.

For ratings, where to stay, and other tourist information, read our San Jose road trip planning app.

The Route module can help you plan travel from Providencia Island to San Jose. The time zone difference moving from Colombia Standard Time (COT) to Central Standard Time (CST) is minus 1 hour. Traveling from Providencia Island in July, things will get little chillier in San Jose: highs are around 31°C and lows about 22°C. Cap off your sightseeing on the 28th (Fri) early enough to go by car to Puerto Viejo de Talamanca.
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Tours · Museums · Parks · Nature
Side Trip
Find places to stay Jul 25 — 28:

Puerto Viejo de Talamanca, Costa Rica — 3 nights

Walaba

Puerto Viejo de Talamanca offers a wealth of entertainment by the sea, attracting a lively international crowd of revelers while maintaining a bright and breezy coastal charm with a local feel.
Take a break from Puerto Viejo de Talamanca with a short trip to Sloth Sanctuary of Costa Rica in Cahuita, about 42 minutes away. Next up on the itinerary: tour the pleasant surroundings at Nature Observatorio, enjoy the sand and surf at Playa Punta Uva, and head outdoors with Outdoor Activities.

For more things to do, where to stay, ratings, and other tourist information, use the Puerto Viejo de Talamanca trip maker website.

Traveling by car from San Jose to Puerto Viejo de Talamanca takes 4 hours. Alternatively, you can take a bus; or take a shuttle. Finish your sightseeing early on the 31st (Mon) so you can drive to Bocas del Toro.
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Parks · Outdoors · Wildlife · Beaches
Side Trips
Find places to stay Jul 28 — 31:

Bocas del Toro, Panama — 3 nights

Bocas del Toro, also known colloquially as Bocas Town, is the capital of the Panamanian province of Bocas del Toro and the district of Bocas del Toro. Bocas del Toro is known for nightlife, wildlife, and outdoors. Your trip includes some of its best attractions: step off the mainland to explore Isla Pajaros and see some colorful creatures with Panama Dive School.

For ratings, other places to visit, traveler tips, and more tourist information, go to the Bocas del Toro day trip app.

You can drive from Puerto Viejo de Talamanca to Bocas del Toro in 3.5 hours. You'll lose 1 hour traveling from Puerto Viejo de Talamanca to Bocas del Toro due to the time zone difference. Cap off your sightseeing on the 3rd (Thu) early enough to catch the flight to Panama City.
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Outdoors · Wildlife · Tours · Parks
Side Trip
Find places to stay Jul 31 — Aug 3:

Panama City, Panama — 2 nights

Dubai of Latin America

Arguably the most modern of Central American cities, Panama City boasts a shimmering skyline of glass skyscrapers.
Kick off your visit on the 4th (Fri): stop by Casco Viejo and then delve into the distant past at Panama La Vieja.

To find where to stay, traveler tips, photos, and other tourist information, read our Panama City trip itinerary planning site.

You can fly from Bocas del Toro to Panama City in 2.5 hours. Alternatively, you can do a combination of ferry and bus. Expect a daytime high around 36°C in August, and nighttime lows around 29°C. Wrap up your sightseeing on the 5th (Sat) to allow time to fly to Cartagena.
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Historic Sites · Neighborhoods
Find places to stay Aug 3 — 5:

Cartagena, Colombia — 3 nights

City of Heroes

The site of the continent's first Spanish colony, Cartagena retains much of its colonial flavor thanks to a World Heritage-listed old town, encircled by old walls and protected by imposing fortresses.
Cartagena is known for historic sites, sightseeing, and museums. Your trip includes some of its best attractions: steep yourself in history at Walled City of Cartagena, take a tour by water with Boat Tours & Water Sports, don't miss a visit to Plaza Santo Domingo, and take in the architecture and atmosphere at Sanctuary of Saint Peter Claver.

To find more things to do, photos, where to stay, and more tourist information, use the Cartagena trip builder.

You can fly from Panama City to Cartagena in 4.5 hours. August in Cartagena sees daily highs of 38°C and lows of 30°C at night. Cap off your sightseeing on the 8th (Tue) early enough to catch the flight to Medellin.
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Historic Sites · Outdoors · Tours · Museums
Find places to stay Aug 5 — 8:

Medellin, Colombia — 2 nights

City of the Eternal Spring

Nestled between rising hills in a narrow valley, Medellin serves as an energetic melting pot of people from all socio-economic classes.
On the 8th (Tue), tour the pleasant surroundings at Parque Arvi, then take an in-depth tour of Museum Pablo Escobar, and then steep yourself in history at Pueblito Paisa. Get ready for a full day of sightseeing on the next day: admire the natural beauty at Jardin Botanico de Medellin, then get the lay of the land with Walking tours, and then let the kids burn off some steam at Parque Lleras.

To see reviews, other places to visit, maps, and more tourist information, use the Medellin day trip planning site.

You can fly from Cartagena to Medellin in 3 hours. Other options are to drive; or take a bus. Plan for a bit cooler temperatures traveling from Cartagena in August, with highs in Medellin at 33°C and lows at 20°C. Cap off your sightseeing on the 10th (Thu) early enough to go by car to Guatape.
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Parks · Tours · Wildlife · Historic Sites
Find places to stay Aug 8 — 10:

Guatape, Colombia — 2 nights

On the shores of a large artificial lake, Guatape ensures a pleasant experience in a quiet little town known for its friendly residents and attractive architecture.
Guatape is known for nature, historic sites, and adventure. Your trip includes some of its best attractions: stroll through Guatape Motos, explore the striking landscape at Piedra Del Penol, take in the waterfront activity at Lanchivas, and pause for some serene contemplation at Iglesia de Nuestra Senora del Carmen.

To see ratings, reviews, more things to do, and tourist information, read Guatape online attractions planner.

Traveling by car from Medellin to Guatape takes 2 hours. Alternatively, you can take a bus. In August, Guatape is little chillier than Medellin - with highs of 26°C and lows of 15°C. Finish up your sightseeing early on the 12th (Sat) so you can go by car to Lima.
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Parks · Outdoors · Nature · Trails
Side Trip
Find places to stay Aug 10 — 12:

Lima, Peru — 2 nights

City of the Kings

Founded in 1535 by Spanish explorer Francisco Pizarro, Lima represents an interesting blend of modern attractions and preserved colonial architecture, much of it clustered in the World Heritage-listed city center.
Start off your visit on the 15th (Tue): visit a coastal fixture at Faro La Marina, get engrossed in the history at Museo Larco, then take an in-depth tour of Museo Convento San Francisco y Catacumbas, and finally make a trip to Plaza de Armas (Plaza Mayor). Get ready for a full day of sightseeing on the next day: steep yourself in history at Huaca Pucllana, take a stroll through Barranco, then shop like a local with Shopping Center Larcomar (Centro Comercial Larcomar), then stroll around Parque Alfredo Salazar, and finally admire the striking features of Palacio de la Union.

Planning Lima trip won't be overwhelming when you use Inspirock's itinerary maker.

Traveling by car from Guatape to Lima takes 54 hours. Expect little chillier weather when traveling from Guatape in August: highs in Lima hover around 22°C, while lows dip to 18°C. Finish your sightseeing early on the 16th (Wed) to allow enough time to fly to Machu Picchu.
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Historic Sites · Museums · Shopping · Neighborhoods
Find places to stay Aug 14 — 16:

Machu Picchu, Peru — 2 nights

A symbol of the Incan civilization, the abandoned city of Machu Picchu represents a must-see on a Peru vacation.
Start off your visit on the 17th (Thu): contemplate the long history of Santuario Historico de Machu Picchu and then stroll through Mandor. Get ready for a full day of sightseeing on the 18th (Fri): get great views at Intipuncu and then indulge in some personalized pampering at Natura Spa Healing Hands.

To see maps, more things to do, ratings, and tourist information, read our Machu Picchu online vacation builder.

You can fly from Lima to Machu Picchu in 3.5 hours. Other options are to drive; or do a combination of bus and taxi. Wrap up your sightseeing on the 18th (Fri) to allow time to fly back home.
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Historic Sites · Wildlife · Parks · Spas
Find places to stay Aug 16 — 18:

Mexico travel guide

4.5
Ruins · Zipline · Beaches
Tailor-made for anyone seeking that traditional sun-and-sand experience, Mexico vacations allow visitors to explore nearly 10,000 km (6,200 mi) of picturesque coastlines. Idyllic beaches and favorable year-round weather aside, this diverse country with a rich pre-Colombian history allows tourists a chance to discover a fascinating cuisine, numerous archaeological sites, state-of-the-art museums, colonial-era haciendas, and outstanding examples of 21st-century architecture. Most visitors get to know the country by its cities, but if you want a well-rounded Mexico tour, spend some time exploring its jungles, cloud forests, Caribbean reefs, snowcapped volcanoes, vast deserts, and tranquil lagoons. Life is lived outdoors in Mexico, so wherever you go, don't forget to dine alfresco and stroll the country's colonial streets.
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Nicaragua travel guide

4.3
Churches · Volcanos · Specialty Museums
Still emerging as a major tourist destination, Nicaragua, the largest country in Central America, entices travelers with its rich history and remarkable natural beauty just waiting to be discovered. A holiday in Nicaragua allows you to explore a vibrant culture, scenic beaches, and plenty of spots off the beaten path. Majestic volcanoes, lakes, and forests offer numerous chances for exploration and exciting adventures, while major cities boast splendid colonial architecture. With access to coastlines on both the Pacific and the Caribbean, a vacation in Nicaragua appeals to those looking for thrilling surfing experiences, dramatic views, or a chance to spread out on a deserted tropical beach.
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