61 days in South America, Central America & Mexico Itinerary

61 days in South America, Central America & Mexico Itinerary

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Make it your trip
+2
Fly to Ezeiza, Shuttle to Terminal Madero, Ferry to Montevideo
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Montevideo, Uruguay
— 3 nights
Drive
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Colonia del Sacramento, Uruguay
— 4 nights
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Ferry to Puerto Madero, Shuttle to Ezeiza, Fly to Uyuni
3
Uyuni, Bolivia
— 2 nights
Fly
4
La Paz, Bolivia
— 3 nights
Fly
5
Cusco, Peru
— 7 nights
Fly
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Lima, Peru
— 6 nights
Fly
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Margarita Island, Venezuela
— 4 nights
Fly
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Cartagena, Colombia
— 6 nights
Fly
9
Bogota, Colombia
— 3 nights
Fly
10
Quito, Ecuador
— 3 nights
+2
Fly to Baltra Island, Fly to San Cristobal, Ferry to Puerto Ayora
11
Puerto Ayora, Ecuador
— 8 nights
+2
Drive to Seymour Airport, Fly to Augusto C. Sandino (Managua) International Airport, Drive to Granada
12
Granada, Nicaragua
— 3 nights
Fly
13
Cancun, Mexico
— 6 nights
Fly

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Montevideo, Uruguay — 3 nights

With a rich cultural scene and plenty of developed beaches, Montevideo vacations appeal to a growing number of visitors from around the world.
Discover out-of-the-way places like Pizzorno Family Estates and Bouza Bodega Boutique. Head to Tres Cruces and Mercado del Puertofor some retail therapy. Venture out of the city with trips to Punta del Este (Conrad Casino & Playa Mansa). The adventure continues: examine the collection at 1972 Museum, don't miss a visit to Plaza Independencia, take in the architecture and atmosphere at Catedral de Montevideo, and explore the world behind art at Palacio Taranco.

To find ratings and other tourist information, read Montevideo day trip planner.

Riyadh, Saudi Arabia to Montevideo is an approximately 30-hour combination of flight, shuttle, and ferry. The time zone difference moving from Arabian Standard Time to Uruguay Standard Time is minus 6 hours. Prepare for much colder weather when traveling from Riyadh in June: high temperatures in Montevideo hover around 19°C and lows are around 7°C. Finish up your sightseeing early on the 25th (Sat) so you can go by car to Colonia del Sacramento.
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Wineries · Neighborhoods · Shopping · Museums
Side Trips
Find places to stay Jun 21 — 25:

Colonia del Sacramento, Uruguay — 4 nights

Sleepy cobbled streets lined with pastel-colored houses lead down to the water in Colonia del Sacramento.
Do some cultural sightseeing at Rambla Colonia Del Sacramento and Basilica De Santisimo Sacramento. Museum-lovers will appreciate Antik Objetos con Alma and Museo Portugues. Step out of Colonia del Sacramento to go to Carmelo and see Bodega Boutique El Legado, which is approximately 1h 15 min away. There's still lots to do: don't miss a visit to La Calle de los Suspiros, wander the streets of Barrio Historico, examine the collection at Museo del Origami, and enjoy the sea views from Colonia del Sacramento Lighthouse.

To find photos, reviews, more things to do, and tourist information, use the Colonia del Sacramento trip site.

You can drive from Montevideo to Colonia del Sacramento in 2.5 hours. Alternatively, you can take a bus. Expect a daytime high around 19°C in June, and nighttime lows around 9°C. Wrap up your sightseeing on the 29th (Wed) to allow time to travel to Uyuni.
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Museums · Historic Sites · Wineries · Neighborhoods
Side Trips
Find places to stay Jun 25 — 29:

Uyuni, Bolivia — 2 nights

Emptiness surrounds the desert outpost of Uyuni, the gateway to the world's largest salt flats.
Kick off your visit on the 30th (Thu): take in the dramatic natural features at Salar de Uyuni and then see the interesting displays at Train Cemetery. Get ready for a full day of sightseeing on the 1st (Fri): head off the coast to Isla Incahuasi.

To see where to stay, more things to do, other places to visit, and other tourist information, read our Uyuni trip planner.

You can do a combination of ferry, shuttle, and flight from Colonia del Sacramento to Uyuni in 13.5 hours. Alternatively, you can do a combination of ferry, shuttle, flight, and bus; or drive. You'll gain 1 hour traveling from Colonia del Sacramento to Uyuni due to the time zone difference. Expect a bit cooler weather when traveling from Colonia del Sacramento in June: highs in Uyuni hover around 8°C, while lows dip to 7°C. Finish up your sightseeing early on the 1st (Fri) so you can catch the flight to La Paz.
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Parks · Nature · Museums
Find places to stay Jun 29 — Jul 1:

La Paz, Bolivia — 3 nights

Take a moment to catch your breath as you commence your holiday in La Paz.
Explore hidden gems such as Adrenaline & Extreme Tours and WMDR Yungas Road. There's lots more to do: make a trip to Mi Teleferico, savor the flavors at Food & Drink, and admire the landmark architecture of Iglesia de San Francisco.

For other places to visit, where to stay, more things to do, and other tourist information, read our La Paz day trip app.

Fly from Uyuni to La Paz in 2.5 hours. Alternatively, you can drive; or take a bus. When traveling from Uyuni in July, plan for a bit warmer days in La Paz, with highs around 17°C, while nights are a bit cooler with lows around -4°C. Cap off your sightseeing on the 4th (Mon) early enough to catch the flight to Cusco.
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Outdoors · Tours · Scenic Drive · Historic Sites
Find places to stay Jul 1 — 4:

Cusco, Peru — 7 nights

Capital of the Inca Empire for three centuries, World Heritage-listed Cusco is now a major tourist destination, drawing nearly 2 million annual tourists with its well-preserved colonial architecture and proximity to Machu Picchu.
Your inner history buff will appreciate Sacsayhuaman and Sacred Valley of the Incas. You'll explore and learn at ChocoMuseo and Centro de Textiles Tradicionales del Cusco. When in Cusco, make a side trip to see Archaeological Park Ollantaytambo in Ollantaytambo, approximately Ollantaytambo away. Spend the 5th (Tue) wandering through the wild on a nature and wildlife tour. Next up on the itinerary: trek along exploor, don't miss a visit to San Blas, take an in-depth tour of Museo de Arte Precolombino, and indulge in some personalized pampering at some of the best spas.

To see reviews, where to stay, photos, and tourist information, read our Cusco sightseeing planner.

Traveling by flight from La Paz to Cusco takes 4.5 hours. Alternatively, you can drive; or take a bus. The time zone changes from Bolivia Time to Peru Standard Time, which is usually a -1 hour difference. Expect somewhat warmer temperatures when traveling from La Paz in July; daily highs in Cusco reach 24°C and lows reach 1°C. Wrap up your sightseeing on the 11th (Mon) early enough to fly to Lima.
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Historic Sites · Outdoors · Tours · Wildlife
Side Trips
Find places to stay Jul 4 — 11:

Lima, Peru — 6 nights

Founded in 1535 by Spanish explorer Francisco Pizarro, Lima represents an interesting blend of modern attractions and preserved colonial architecture, much of it clustered in the World Heritage-listed city center.
Shop till you drop at Shopping Center Larcomar (Centro Comercial Larcomar) and Jade Rivera World. Centro Historico de Lima and Museo Convento San Francisco y Catacumbas will appeal to history buffs. Next up on the itinerary: contemplate the long history of Basilica y Monasterio de Santo Domingo, view the masterpieces at Jade Rivera Museum, delve into the distant past at Huaca Pucllana, and don't miss a visit to Plaza de Armas (Plaza Mayor).

For traveler tips, reviews, more things to do, and tourist information, read our Lima online route planner.

You can fly from Cusco to Lima in 3.5 hours. Other options are to drive; or take a bus. Traveling from Cusco in July, you can expect nighttime temperatures to be warmer in Lima, with lows of 19°C. You'll set off for Margarita Island on the 17th (Sun).
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Museums · Shopping · Historic Sites · Neighborhoods
Side Trip
Find places to stay Jul 11 — 17:

Margarita Island, Venezuela — 4 nights

A popular holiday spot for Venezuelans, sunny Margarita Island boasts an exotic Caribbean location, but at the same time is easily accessible from the mainland.
Visit Playa el Yaque and Playa El Agua for some beach relaxation. Get some historical perspective at Basilica Nuestra Senora Del Valle and Fortín La Galera. Spend the 18th (Mon) exploring nature at Laguna de la Restinga. There's more to do: look for gifts at Sambil Margarita.

For maps, photos, reviews, and more tourist information, use the Margarita Island road trip planning website.

Traveling by flight from Lima to Margarita Island takes 10 hours. Alternatively, you can do a combination of car and ferry. Due to the time zone difference, you'll lose 1 hour traveling from Lima to Margarita Island. While traveling from Lima, expect warmer days and a bit warmer nights in Margarita Island, ranging from highs of 38°C to lows of 30°C. Wrap up your sightseeing on the 21st (Thu) to allow time to fly to Cartagena.
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Parks · Nature · Historic Sites · Beaches
Find places to stay Jul 17 — 21:

Cartagena, Colombia — 6 nights

The site of the continent's first Spanish colony, Cartagena retains much of its colonial flavor thanks to a World Heritage-listed old town, encircled by old walls and protected by imposing fortresses.
Shop till you drop at NH Galeria and Dantas Store. You'll explore the less-touristy side of things at Scuba & Snorkeling and Barrio Getsemani. The adventure continues: steep yourself in history at Torre del Reloj, take in the architecture and atmosphere at Sanctuary of Saint Peter Claver, see the interesting displays at Caribe Jewelry Museum & Factory, and make a trip to Plaza Santo Domingo.

To see photos, more things to do, and tourist information, use the Cartagena travel route app.

You can fly from Margarita Island to Cartagena in 9 hours. Alternatively, you can do a combination of car and ferry. The time zone difference moving from Venezuela Time to Colombia Standard Time is minus 1 hour. In July in Cartagena, expect temperatures between 38°C during the day and 30°C at night. Wrap up your sightseeing on the 27th (Wed) early enough to fly to Bogota.
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Historic Sites · Tours · Wildlife · Outdoors
Find places to stay Jul 21 — 27:

Bogota, Colombia — 3 nights

Colombia's heart and soul, Bogota has earned the nickname "Athens of South America" thanks to its abundance of universities, libraries, and lower-level schools.
Visit Catedral de Sal de Zipaquira and Catedral Diocesana for their historical value. Appreciate the collections at Barrio La Candelaria and Museo Botero del Banco de la Republica. Explore the numerous day-trip ideas around Bogota: Museo Aeroespacial Fuerza Aerea Colombiana (in Tocancipa) and Laguna de Guatavita (in Tierra Negra).

For where to stay, more things to do, and other tourist information, refer to the Bogota online trip builder.

Traveling by flight from Cartagena to Bogota takes 3 hours. Alternatively, you can drive; or take a bus. Prepare for much colder weather when traveling from Cartagena in July: high temperatures in Bogota hover around 21°C and lows are around 10°C. Finish your sightseeing early on the 30th (Sat) to allow enough time to fly to Quito.
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Museums · Historic Sites · Beaches · Outdoors
Side Trips
Find places to stay Jul 27 — 30:

Quito, Ecuador — 3 nights

High in the Andean foothills, Quito remains one of the world's most photogenic capital cities, featuring two dramatic mountain ranges as its backdrop.
Museum-lovers will get to explore Intinan Museum and Museo Etnohistorico de Artesanias del Ecuador Mindalae. Get some cultural insight at Quito Old Town and Iglesia y Convento de San Francisco. There's much more to do: contemplate in the serene atmosphere at Basilica del Voto Nacional, admire the striking features of Fundacion Iglesia de la Compania, see the interesting displays at Museo Camilo Egas, and take an in-depth tour of Museo Templo del Sol Pintor Ortega Maila.

To see reviews, where to stay, other places to visit, and more tourist information, you can read our Quito tour builder tool.

You can fly from Bogota to Quito in 5 hours. Other options are to drive; or take a bus. Traveling from Bogota in July, things will get a bit warmer in Quito: highs are around 26°C and lows about 17°C. Wrap up your sightseeing by early afternoon on the 2nd (Tue) to allow time for travel to Puerto Ayora.
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Historic Sites · Museums · Shopping
Find places to stay Jul 30 — Aug 2:

Puerto Ayora, Ecuador — 8 nights

The largest settlement in the Galapagos, Puerto Ayora offers visitors to the islands an array of facilities and things to do.
You'll get in some beach time at Galapagos Beach at Tortuga Bay and Playa de los Alemanes. Give yourself a bit of retail therapy at Samay Latin Art and Maki-Art Gallery. The adventure continues: stroll through El Chato - Giant Tortoise Reserve, explore the striking landscape at Las Grietas, view the masterpieces at Galeria Exotico Ecuador, and kick back and relax at Playa de los Perros.

For photos, more things to do, traveler tips, and other tourist information, go to the Puerto Ayora trip itinerary app.

Getting from Quito to Puerto Ayora by combination of flight and ferry takes about 9 hours. Plan for somewhat warmer nights when traveling from Quito in August since evenings lows in Puerto Ayora dip to 24°C. Wrap up your sightseeing on the 10th (Wed) to allow time to travel to Granada.
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Parks · Outdoors · Wildlife · Beaches
Side Trip
Find places to stay Aug 2 — 10:

Granada, Nicaragua — 3 nights

The lakeside city of Granada has the look and feel of a historically important economic and political center, with grand colonial architecture, a unified look, and many cultural attractions.
You'll explore and learn at Centro Cultural Antiguo Convento San Francisco and Casa de Los Tres Mundos. Deepen your sense of the past at sights like Catedral de Granada and Iglesia de La Merced. Go for a jaunt from Granada to Ticuantepe to see Montibelli Private National Reserve about 40 minutes away. It doesn't end there: get a taste of the local shopping with Soy Nica.

To see ratings, other places to visit, more things to do, and tourist information, go to the Granada online travel route planner.

Explore your travel options from Puerto Ayora to Granada with the Route module. You'll gain 1 hour traveling from Puerto Ayora to Granada due to the time zone difference. On the 13th (Sat), wrap the sightseeing up by early afternoon so you can fly to Cancun.
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Museums · Historic Sites · Wildlife · Parks
Side Trip
Find places to stay Aug 10 — 13:

Cancun, Mexico — 6 nights

Few destinations in Mexico dazzle visitors quite like Cancun, a modern resort town filled with glitzy hotels sitting on picturesque and well-developed Caribbean beaches.
Head to La Isla Shopping Village and Tattoo Studio Hennafor plenty of shopping. Get outdoors at Ecopark Kantun Chi and National Reef Park of Puerto Morelos. Explore the numerous day-trip ideas around Cancun: Playa del Carmen (3D Museum of Wonders, Parque Los Fundadores, &more) and Isla Mujeres (Playa El Centro & Punta Sur). The adventure continues: relax and rejuvenate at some of the best spas, identify plant and animal life at Wildlife Areas, tour the pleasant surroundings at Playa Delfines, and explore the ancient world of Zona Arqueologica El Rey.

To find ratings, reviews, maps, and more tourist information, use the Cancun day trip app.

Getting from Granada to Cancun by flight takes about 7.5 hours. Other options: drive; or do a combination of shuttle, bus, taxi, and ferry. Traveling from Granada to Cancun, you'll lose 1 hour due to the time zone difference. August in Cancun sees daily highs of 37°C and lows of 28°C at night. Finish your sightseeing early on the 19th (Fri) so you can fly back home.
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Parks · Outdoors · Wildlife · Beaches
Side Trips
Find places to stay Aug 13 — 19:

Uruguay travel guide

4.1
Landmarks · Scenic Walking Areas · Architectural Buildings
Switzerland of South America
One of the smallest countries in South America, tourist-friendly Uruguay is often called the "Switzerland of South America" because of its consistent economic development and progressive society. Open-minded Montevideo serves as the starting point of most Uruguay vacations, offering visitors an eclectic cultural scene and a chance to discover some of South America's major architectural treasures. Away from the cosmopolitan capital city, vacations in Uruguay involve exploring wildlife-rich areas along the Atlantic and touring the rustic interior on horseback, gaucho style. In this sports-loving country, the highlight of your Uruguay trip might just be a soccer match between Penarol and Nacional, the country's two major clubs.
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Bolivia travel guide

4.2
Landmarks · Geologic Formations · Specialty Museums
Tibet of the Americas
If you're an adventurous tourist, consider adding a Bolivia vacation to your travel itinerary. A land of rainforests, Andean glaciers, high altitude cities, and rushing rivers, Bolivia remains one of the most remote countries in the Western Hemisphere. With 60 percent of the population made up of indigenous peoples, native cultures permeate thecountry's music, architecture, and arts, as well as local folklore and traditions. Traveling in Bolivia you can experience diverse wildlife and ecosystems, learn about the country's rich history, try out its distinctive cuisine, and practice your Spanish with the locals, known for their clean and easy-to-understand accent.
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Peru travel guide

4.6
Historic Sites · Parks · Landmarks
Land of the Incas
In a country renowned for its pre-Columbian archeological sites, no Peru vacation would be complete without an adrenaline-inducing hike to Machu Picchu, World Heritage-listed symbol of the once-mighty Incan Empire. Aside from visiting these spectacular ruins set against the backdrop of photogenic mountain peaks, most holidays in Peru also include an exploration of the country's pretty cities, boasting well-preserved colonial architecture and a slew of modern buildings housing fine museums, galleries, shops, and restaurants. Ideal for active vacationers, Peru trips are also tailor-made for gourmands, as the country's eclectic cuisine blends tasty influences from Africa, Asia, and Europe.
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Venezuela travel guide

4.1
Beaches · Landmarks · Gift & Specialty Shops
Land of Grace
A vacation in Venezuela, one of the most biodiverse countries on the planet, can be both affordable and highly rewarding. From snowcapped mountains and vast grassland, to tropical islands and lush rainforests, Venezuela's varied landscapes are a paradise for nature lovers. Whether you're looking to laze on the Caribbean beaches, trek through the verdant jungles, or immerse yourself in the vibrant city culture, a Venezuela holiday offers something for everyone. Admire the world's highest waterfalls, go island hopping, discover tasty local delicacies, and witness the sheer abundance of wildlife and endemic species in Venezuela.
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Colombia travel guide

4
Historic Sites · Landmarks · Beaches
Diverse in terms of landscapes, climates, and cultures, Colombia remains one of South America's least explored tourist destinations, overshadowed by its more popular southern neighbors. Combining the best of what the continent has to offer, a vacation in Colombia allows you to blend outdoor adventures with tours of picture-perfect cobblestoned towns dating back to the colonial era. Tourists on a Colombia holiday can easily hop from sun-kissed coastal spots to the hilly coffee-growing region, where thriving plantations quickly give way to a landscape of snow-covered volcanic peaks and the paramo--alpine ecosystems sheltering some of the rarest plants growing above the continuous forest line.
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Ecuador travel guide

4.5
Architectural Buildings · Landmarks · History Museums
With abundant opportunities to discover fascinating World Heritage Sites, a holiday in Ecuador remains among the most culturally enriching travel experiences. Home to the world's highest active volcano, this little country packs a big punch when it comes to tourist activities. Some of the most popular things to do in Ecuador include visits to its astonishingly biodiverse wilderness areas, home to some 1,500 bird species, 840 species of amphibians and reptiles, and nearly 20,000 plant species. Of course, the highlight of many Ecuador vacations is bound to be the Galapagos Islands, made famous by naturalist Charles Darwin. Aside from the stunning nature, Ecuador also boasts many historic cities filled with photogenic colonial-era churches, mansions, and plazas.
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Nicaragua travel guide

4.3
Churches · Volcanos · Specialty Museums
Still emerging as a major tourist destination, Nicaragua, the largest country in Central America, entices travelers with its rich history and remarkable natural beauty just waiting to be discovered. A holiday in Nicaragua allows you to explore a vibrant culture, scenic beaches, and plenty of spots off the beaten path. Majestic volcanoes, lakes, and forests offer numerous chances for exploration and exciting adventures, while major cities boast splendid colonial architecture. With access to coastlines on both the Pacific and the Caribbean, a vacation in Nicaragua appeals to those looking for thrilling surfing experiences, dramatic views, or a chance to spread out on a deserted tropical beach.
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Mexico travel guide

4.5
Ruins · Zipline · Beaches
Tailor-made for anyone seeking that traditional sun-and-sand experience, Mexico vacations allow visitors to explore nearly 10,000 km (6,200 mi) of picturesque coastlines. Idyllic beaches and favorable year-round weather aside, this diverse country with a rich pre-Colombian history allows tourists a chance to discover a fascinating cuisine, numerous archaeological sites, state-of-the-art museums, colonial-era haciendas, and outstanding examples of 21st-century architecture. Most visitors get to know the country by its cities, but if you want a well-rounded Mexico tour, spend some time exploring its jungles, cloud forests, Caribbean reefs, snowcapped volcanoes, vast deserts, and tranquil lagoons. Life is lived outdoors in Mexico, so wherever you go, don't forget to dine alfresco and stroll the country's colonial streets.
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